… relapsing-remitting multiple sclerosis after 24 doses of natalizumab: evidence from an Italian spontaneous, prospective, and observational study (the TY-STOP Study)

M Clerico, I Schiavetti, SF De Mercanti, F Piazza… - JAMA …, 2014 - jamanetwork.com
… Herein, we describe the results of a spontaneous, prospective, multicenter, observational
study aimed at evaluating MS clinical activity, determined by the mean annualized relapse rate …

Italian multicentre observational study of the prevalence of CCSVI in multiple sclerosis (CoSMo study): rationale, design, and methodology

G Comi, MA Battaglia, A Bertolotto, M Del Sette… - Neurological …, 2013 - Springer
… , Italian Multiple sclerosis Foundation), this is a multicentric, observational study which …
, the multicentric design, and the validation of the diagnostic criteria are what distinguish this …

Long-term follow-up of pediatric MS patients starting treatment with injectable first-line agents: a multicentre, Italian, retrospective, observational study

D Baroncini, M Zaffaroni, L Moiola… - Multiple Sclerosis …, 2019 - journals.sagepub.com
… open label observational studies. So… study was authorized by the ethical committee of the
coordinating center. Given the retrospective observational study design, according to the Italian

A cross-sectional, multicentre study of the therapeutic management of multiple sclerosis relapses in Italy

P Annovazzi, V Tomassini, B Bodini, L Boffa… - Neurological …, 2013 - Springer
… 13 multiple sclerosis centres completed a questionnaire every time they assessed multiple
sclerosis … Our study confirms the therapeutic attitude of multiple sclerosis specialists in treating …

Observational case-control study of the prevalence of chronic cerebrospinal venous insufficiency in multiple sclerosis: results from the CoSMo study

…, CoSMo Collaborative Study Group - Multiple Sclerosis …, 2013 - journals.sagepub.com
… The primary end-point of this multicentric, case-control study … objective of the CoSMo study,
named after the Italian words ‘‘… Observational Study of the prevalence of CCSVI in multiple

Half-dose fingolimod for treating relapsing-remitting multiple sclerosis: observational study

C Zecca, A Merlini, G Disanto… - Multiple Sclerosis …, 2018 - journals.sagepub.com
Multicentre retrospective observational study. Clinical, laboratory and neuroimaging data
were consecutively collected from 60 FTY-EOD and 63 FTY-ED patients. Baseline …

Rituximab in the treatment of Neuromyelitis optica: a multicentre Italian observational study

P Annovazzi, M Capobianco, L Moiola, F Patti… - Journal of …, 2016 - Springer
… Some authors replicated the infusion schedule utilized in Multiple Sclerosis (1000 mg, 2
weeks apart) [25], some others administered RTX at the dose of 375 mg/m 2 of Body Surface …

Treatment of multiple sclerosis with rituximab: a multicentric Italian–Swiss experience

C Zecca, F Bovis, G Novi… - Multiple Sclerosis …, 2020 - journals.sagepub.com
… Consistently with other observational studies, our data show effectiveness of … a multicenter,
retrospective study based on prospectively collected data, involving 1 Swiss and 22 Italian

Fingolimod Treatment in Relapsing‐Remitting Multiple Sclerosis Patients: A Prospective Observational Multicenter Postmarketing Study

R Totaro, C Di Carmine, G Costantino… - Multiple sclerosis …, 2015 - Wiley Online Library
… postmarketing multicenter observational study was to … of our study was to provide real world
efficacy data from patients representative of the Italian relapsing-remitting multiple sclerosis

Cancer risk for multiple sclerosis patients treated with azathioprine and disease-modifying therapies: an Italian observational study

L La Mantia, MD Benedetti, M Sant, A d'Arma… - Neurological …, 2021 - Springer
… Long-term safety update for chronic therapies is further necessary in clinical setting [9],
observational studies being the design of choice for the detection of rare, delayed, and/or …