[HTML][HTML] Efficacy and safety of erlotinib monotherapy for Japanese patients with advanced non-small cell lung cancer: a phase II study

K Kubota, Y Nishiwaki, T Tamura, K Nakagawa… - Journal of Thoracic …, 2008 - Elsevier
… a phase I study of erlotinib in Japanese patients with solid tumors, 15 which showed erlotinib
to be well tolerated at a dose of 150 mg/d, as well as a phase II study of erlotinib in NSCLC …

[HTML][HTML] Erlotinib plus bevacizumab vs erlotinib monotherapy as first-line treatment for advanced EGFR mutation-positive non-squamous non-small-cell lung cancer …

N Yamamoto, T Seto, M Nishio, K Goto, I Okamoto… - Lung Cancer, 2021 - Elsevier
… Firstly, our study enrolled only Japanese patients, therefore we await the results of other …
patients treated with the combination of erlotinib plus bevacizumab in countries other than Japan

Erlotinib for Japanese Patients with Activating EGFR Mutation-Positive Non-Small-Cell Lung Cancer: Combined Analyses from Two Phase II Studies

S Atagi, K Goto, T Seto, N Yamamoto, T Tamura… - Future …, 2016 - Taylor & Francis
… designed to investigate erlotinib for the first-line treatment of Japanese patients with EGFR
… -line erlotinib monotherapy had a favorable efficacy and safety profile in Japanese patients

[HTML][HTML] A phase II trial of erlotinib monotherapy in pretreated patients with advanced non-small cell lung cancer who do not possess active EGFR mutations: Okayama …

H Yoshioka, K Hotta, K Kiura, N Takigawa… - Journal of Thoracic …, 2010 - Elsevier
… by the Japanese government, and few agents are available in the salvage setting in Japan.
… a phase II trial of erlotinib monotherapy in Japanese patients with relapsed NSCLC who did …

[HTML][HTML] A phase II trial of erlotinib monotherapy for pretreated elderly patients with advanced EGFR wild-type non-small cell lung cancer

H Minemura, H Yokouchi, K Azuma, K Hirai… - BMC Research …, 2015 - Springer
… The frequency of skin-related adverse events in the current study was comparable to the
frequency of skin disorders reported in a large-scale erlotinib-treated Japanese cohort [24]. In …

Phase II study of erlotinib as third-line monotherapy in patients with advanced non-small-cell lung cancer without epidermal growth factor receptor mutations

S Matsuura, N Inui, Y Ozawa… - Japanese Journal of …, 2011 - academic.oup.com
… of erlotinib-naïve subjects, erlotinib is recommended as third-line therapy. However, the
efficacy of erlotinib as third-line chemotherapy for Japanese patients … of erlotinib in patients with …

Phase III study comparing bevacizumab plus erlotinib to erlotinib in patients with untreated NSCLC harboring activating EGFR mutations: NEJ026.

…, M Maemondo, North East Japan Study Group - 2018 - ascopubs.org
… (NSCLC) had been focused on monotherapy of gefitinib, erlotinib, or afatinib. Combinations
… combination with erlotinib (150 mg daily) plus bevacizumab (15 mg/kg iv q3w) or erlotinib (…

A prospective, multicenter phase II trial of low-dose erlotinib monotherapy for patients with previously treated non-small cell lung cancer (NSCLC) with activating …

Y Nakahara, Y Hosomi, K Yamada, H Okamoto, T Kato… - 2014 - ascopubs.org
… Since the steady-state plasma trough concentration of erlotinib is approximately … erlotinib
may be as effective as full-dose therapy, with less toxicity and cost. Methods: Eligible patients

Phase II study of erlotinib in Japanese patients with advanced non-small cell lung cancer

T Takahashi, N Yamamoto, T Nukiwa, K Mori… - Anticancer …, 2010 - ar.iiarjournals.org
… to the clinical efficacy of erlotinib in patients with NSCLC (14-… and safety of erlotinib in
Japanese patients with relapsed or … safety of erlotinib monotherapy for Japanese patients with …

Clinical utility of erlotinib for the treatment of non-small-cell lung cancer in Japanese patients: current evidence

Y Togashi, H Hayashi, K Nakagawa… - Drug design …, 2014 - Taylor & Francis
Japanese treatment guidelines recommend gefitinib or erlotinib monotherapy for patients
with EGFR-mutated NSCLC. A recent Japanese Phase III trial directly comparing gefitinib and …