… period of 24 weeks (MUSASHI) followed by an open-label extension period of 84 weeks in
Japanese patients with RA. The protocol was approved by the Japanese Ministry of Health, …

… trials for patients with RA in Japan, tocilizumab monotherapy has … in patients who responded
to tocilizumab, almost no patients … In this study tocilizumab in monotherapy for 24 weeks …

… tocilizumab and all tumor necrosis factor inhibitors are effective at slowing X-ray progression.
As monotherapy, adalimumab, etanercept, and tocilizumab … Japan involving 7,901 patients. …

… Research Group of Intractable Vasculitis, Ministry of Health, Labor, and Welfare of Japan.
Risk factors associated with relapse in Japanese patients with microscopic polyangiitis. …

… Furthermore, a phase 2 RCT in Japanese patients who had an inadequate response to …
of tofacitinib monotherapy versus placebo for the treatment of RA in Japanese patients who …

… performed in Japan. Patients were administered TCZ (4 or 8 mg/kg) monotherapy or placebo
… Japanese patient cohort (between 1.46; 95%CI = 1.32–1.60 and 1.90; 95%CI: 1.75–2.07). …

… Tocilizumab monotherapy was compared with MTX in the Study of Active controlled TOcilizumab
monotherapy for Rheumatoid arthritis patients … 5] in Japanese patients refractory to MTX …

… This study investigated the safety and efficacy of tocilizumab monotherapy (8 mg/kg) …
The safety profiles of tocilizumab monotherapy for Japanese RA patients obtained from six …

… for RA patients and is used alone (monotherapy) or … Japanese study than what was reported
by a US study, suggesting that a lower dose of MTX may be sufficient for Japanese patients […

… Tocilizumab was administered by the method approved by the Japanese Ministry of Health,
… However, patients in the TCZ monotherapy group showed a gradual improvement in terms …