… sequence of the human AXIN2 gene, we designed two … bp fragment in exon 1 of the AXIN2
gene. Reaction mixture (20 μl… polymerase (Takara, Kyoto, Japan). The PCR amplification was …

… AXIN2 gene comprises 10 exons encoding an 843-amino acid protein, is located on chromosome
17q24 in humans.14 Loss of heterozygosity of AXIN2 gene … genetic variants in AXIN2 …

… a Japanese population and a Turkish population (21,23), we did not observe any association
in our study population, … this region of AXIN2 was similar to that of the Japanese population. …

… population, other studies have demonstrated a significant association between the
rs2240308 SNP and lung cancer development in Japanese (14) and Turkish (15) populations. …

… Tumor-specific mutations of Axin2 gene have not been reported in lung … Axin2 exon1 T148C
SNP polymorphism and lung cancer in a Japanese population [13] and a Turkish population …

… In our study, we used five genetic models to evaluate the correlation of AXIN2 gene
polymorphisms and cancer risk, including allele contrast model (B vs. A), homozygote comparison …

… Thus, the genetic variations that affect AXIN2 gene may be … regions of AXIN2 gene in PC in
a Turkish population to further … on the protein in a Japanese population [30] but Gunes et al., …

… Elevated levels of β-catenin were certainly attributed to the decreased expression of Axin2
… silencing of Axin2 gene. There are no findings about the specific mutations in Axin2 gene in …

… Wang et al., (2008) examined a number of SNPs in the AXIN2 gene including the four variants
in … In a Japanese population a SNP at codon 50 of the AXIN2 gene was shown to have a …

… population was comprised of a missense mutation (rs2240308) in exon 2 of the AXIN2 gene…
/P in non-Asian and European populations, and in the overall combined populations as well. …