Apixaban for the treatment of Japanese subjects with acute venous thromboembolism (AMPLIFY-J Study)

M Nakamura, M Nishikawa, I Komuro, I Kitajima… - Circulation …, 2015 - jstage.jst.go.jp
… for the initial and long-term treatment of VTE. Moreover, it would … Excellence indicated that
apixaban could be considered a … efficacy of apixaban in Japanese acute PE/DVT subjects with …

Safety and Efficacy of the Oral Direct Factor Xa Inhibitor Apixaban in Japanese Patients With Non-Valvular Atrial Fibrillation–The ARISTOTLE-J Study–

S Ogawa, Y Shinohara, K Kanmuri - Circulation Journal, 2011 - jstage.jst.go.jp
… Randomized, parallel group, warfarin control, multicenter phase II study evaluating safety
of DU-176b in Japanese subjects with non-valvular atrial fibrillation (NVAF). J Thromb …

Randomized, double-blind trial to evaluate the safety of apixaban with antiplatelet therapy after acute coronary syndrome in Japanese patients (APPRAISE-J)

H Ogawa, S Goto, M Matsuzaki, S Hiro, D Shima… - Circulation …, 2013 - jstage.jst.go.jp
… -defined major or CRNM bleeding for Japanese subjects is 3.0% in the placebo group and
ranges from 5.7% to 7.9% in the apixaban groups, this sample size provides the precision of …

Population pharmacokinetics and pharmacogenomics of apixaban in Japanese adult patients with atrial fibrillation

S Ueshima, D Hira, Y Kimura, R Fujii… - British journal of …, 2018 - Wiley Online Library
Japanese AF patients in our study is slightly lower than that in healthy male Japanese subjects
35… Therefore, the racial and pathological differences among AF patients or subjects were …

Safety and effectiveness of apixaban in comparison to warfarin in patients with nonvalvular atrial fibrillation: a propensity-matched analysis from Japanese …

S Kohsaka, J Katada, K Saito… - … Medical Research and …, 2018 - Taylor & Francis
Full article: Safety and effectiveness of apixaban in comparison to warfarin in patients with
nonvalvular atrial fibrillation: a propensity-matched analysis from Japanese administrative …

Pharmacokinetics of anticoagulants apixaban, dabigatran, edoxaban and rivaroxaban in elderly Japanese patients with atrial fibrillation treated in one general …

M Yamazaki-Nishioka, M Kogiku, M Noda, S Endo… - Xenobiotica, 2019 - Taylor & Francis
Full article: Pharmacokinetics of anticoagulants apixaban, dabigatran, edoxaban and rivaroxaban
in elderly Japanese patients with atrial fibrillation treated in one general hospital Skip …

Safety and Effectiveness of Apixaban in Japanese Patients With Venous Thromboembolism in Clinical Practice―A Post-Marketing Surveillance―

N Yamada, M Mo, A Ohsawa, M Sato… - Circulation …, 2021 - jstage.jst.go.jp
Japanese patients newly initiated on apixaban for treatment of VTE or prevention of recurrent
treated with apixaban and patients who had received prior treatment with apixaban were …

[HTML][HTML] Study design of J-ELD AF: a multicenter prospective cohort study to investigate the efficacy and safety of apixaban in Japanese elderly patients

M Akao, T Yamashita, K Okumura… - Journal of …, 2016 - Elsevier
… On such occasions, sufficient consideration should be given not to include information
which can identify subjects, such as the name of subjects. Furthermore, the data on subjects

Bleeding risk of apixaban, dabigatran, and low-dose rivaroxaban compared with warfarin in Japanese patients with non-valvular atrial fibrillation: a propensity …

S Kohsaka, T Murata, N Izumi, J Katada… - … medical research and …, 2017 - Taylor & Francis
… The risk of any bleeding was significantly lower for apixaban (… Japanese patients with NVAF,
treatment with apixaban 5/2.5 … Treatment with dabigatran 150/110 mg BID or rivaroxaban 15…

Evaluation of the single-dose pharmacokinetics and pharmacodynamics of apixaban in healthy Japanese and Caucasian subjects

C Frost, A Shenker, S Jhee, Z Yu, J Wang… - Clinical …, 2018 - Taylor & Francis
… The most frequently reported treatment-emergent AE in this … subjects and one Japanese
subject who received apixaban, as well as one Caucasian subject and one Japanese subject