p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents
X Sui, N Kong, LI Ye, W Han, J Zhou, Q Zhang, C He… - Cancer letters, 2014 - Elsevier
… and apoptosis in response to genotoxic stress. Our increased understanding of the role
of p38 and JNK MAPK pathways in regulating the balance of autophagy and apoptosis will …
of p38 and JNK MAPK pathways in regulating the balance of autophagy and apoptosis will …
Understanding MAPK signaling pathways in apoptosis
J Yue, JM López - International journal of molecular sciences, 2020 - mdpi.com
… The stress-activated JNKs and p38 MAPKs play key roles in balancing cell survival and
death in response to both extracellular and intracellular stresses (reviewed in [12]). Extensive …
death in response to both extracellular and intracellular stresses (reviewed in [12]). Extensive …
Chlorpyrifos induces apoptosis in rat cortical neurons that is regulated by a balance between p38 and ERK/JNK MAP kinases
A Caughlan, K Newhouse, UK Namgung… - Toxicological …, 2004 - academic.oup.com
… Furthermore, we implicate several MAP kinase signaling pathways in chlorpyrifos-… MAP
kinase signaling pathways are involved in the regulation of chlorpyrifos-induced apoptosis, we …
kinase signaling pathways are involved in the regulation of chlorpyrifos-induced apoptosis, we …
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
Z Xia, M Dickens, J Raingeaud, RJ Davis… - Science, 1995 - science.org
… Therefore, the dynamic balance between growth factor-activated … MAP kinase signaling
pathway in apoptosis. To investigate the importance of the p38 MAP kinase pathway for apoptosis…
pathway in apoptosis. To investigate the importance of the p38 MAP kinase pathway for apoptosis…
Antagonistic control of cell fates by JNK and p38-MAPK signaling
T Wada, E Stepniak, L Hui, A Leibbrandt… - Cell Death & …, 2008 - nature.com
… , oppositely control cellular proliferation, regeneration, senescence, and oncogenic
transformation, and that qthe balance between two pathways determines cell fates in response to a …
transformation, and that qthe balance between two pathways determines cell fates in response to a …
MAPK signaling pathways in the regulation of hematopoiesis
CR Geest, PJ Coffer - Journal of leukocyte biology, 2009 - academic.oup.com
… factor in regulating the ultimate balance among expansion, survival, … JNK proteins were first
identified as kinases that were activated by a stress- and apoptosis-inducing agent, JNKs are …
identified as kinases that were activated by a stress- and apoptosis-inducing agent, JNKs are …
… and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway …
K Saeki, N Kobayashi, Y Inazawa, H Zhang… - Biochemical …, 2002 - portlandpress.com
… intracellular signalling pathways for apoptosis induced by … two apoptosis-regulating
mitogen-activated protein (MAP) kinases, namely c-Jun N-terminal kinase (JNK) and p38 MAP kinase…
mitogen-activated protein (MAP) kinases, namely c-Jun N-terminal kinase (JNK) and p38 MAP kinase…
Integrated activation of MAP3Ks balances cell fate in response to stress
AM Winter‐Vann, GL Johnson - Journal of cellular biochemistry, 2007 - Wiley Online Library
… A transient activation of JNK or p38, for example, might have a protective effect in a cellular
… of the same MAPK might lead to a commitment to apoptosis. The concentration of the …
… of the same MAPK might lead to a commitment to apoptosis. The concentration of the …
Inhibition of p38 MAPK sensitizes tumour cells to cisplatin‐induced apoptosis mediated by reactive oxygen species and JNK
L Pereira, A Igea, B Canovas, I Dolado… - EMBO molecular …, 2013 - embopress.org
… Since JNK signalling plays an important role in apoptosis induction (Davis, 2000), we … this
pathway was implicated in the enhanced apoptosis observed upon p38 MAPK inhibition. We …
pathway was implicated in the enhanced apoptosis observed upon p38 MAPK inhibition. We …
JNK, but not MAPK, activation is associated with Fas‐mediated apoptosis in human T cells
DJ Wilson, KA Fortner, DH Lynch… - European journal of …, 1996 - Wiley Online Library
… apoptosis, is blocked by increased levels of CAMP. The balance between proliferation and
apoptosis by … TCR activation of the RadRaf-l/MAPK pathway versus JNK activation by Fas. …
apoptosis by … TCR activation of the RadRaf-l/MAPK pathway versus JNK activation by Fas. …
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