Signal integration by JNK and p38 MAPK pathways in cancer development
EF Wagner, ÁR Nebreda - Nature Reviews Cancer, 2009 - nature.com
… pathways for tumorigenesis in various organs. The expression or activity of JNK and p38
MAPK pathway … defining the functions of the JNK and p38 MAPK pathways in different cancers. …
MAPK pathway … defining the functions of the JNK and p38 MAPK pathways in different cancers. …
MAP kinase pathways activated by stress: the p38 MAPK pathway
T Obata, GE Brown, MB Yaffe - Critical care medicine, 2000 - journals.lww.com
… upstream of the JNK and p38 MAPK cascades. The p38 MAPK and JNK pathways can be
activated … negative constructs of Rac or Cdc42 inhibit p38 MAPK and JNK activation (41, 42) . …
activated … negative constructs of Rac or Cdc42 inhibit p38 MAPK and JNK activation (41, 42) . …
p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents
X Sui, N Kong, LI Ye, W Han, J Zhou, Q Zhang, C He… - Cancer letters, 2014 - Elsevier
… p38 MAPK and JNK pathway. A number of representative up and downstream targets are
shown. Both p38 MAPK and JNK … suggested that MAPK, especially p38 MAPK and JNK, play a …
shown. Both p38 MAPK and JNK … suggested that MAPK, especially p38 MAPK and JNK, play a …
Inhibition of the p38 pathway upregulates macrophage JNK and ERK activities, and the ERK, JNK, and p38 MAP kinase pathways are reprogrammed during …
JP Hall, RJ Davis - Journal of cellular biochemistry, 2002 - Wiley Online Library
… In the present work, we demonstrate that JNK, ERK, and p38 MAP kinase activities are
reprogrammed during the IL-6-induced, macrophage-like differentiation of the murine myeloid M1 …
reprogrammed during the IL-6-induced, macrophage-like differentiation of the murine myeloid M1 …
Regulation of JNK and p38 MAPK in the immune system: signal integration, propagation and termination
… components of the MAPK pathway that facilitate the activation and propagation of MAPK
signaling in immune responses. Moreover, MAPK activity is negatively regulated by MAPK …
signaling in immune responses. Moreover, MAPK activity is negatively regulated by MAPK …
The p38 MAP kinase pathway and its biological function
L New, J Han - Trends in cardiovascular medicine, 1998 - Elsevier
… Thus, the p38 MAP kinase cascade may consist of the sequence: MEKK5’… JNK pathway
plays a role in upregulating the gene expression. As already mentioned here, the p38 pathway …
plays a role in upregulating the gene expression. As already mentioned here, the p38 pathway …
[HTML][HTML] Antagonistic control of cell fates by JNK and p38-MAPK signaling
T Wada, E Stepniak, L Hui, A Leibbrandt… - Cell Death & …, 2008 - nature.com
… Here we report that JNK and p38-MAPK pathways antagonistically control cellular
senescence, oncogenic transformation, and proliferation in primary mouse embryonic fibroblasts (…
senescence, oncogenic transformation, and proliferation in primary mouse embryonic fibroblasts (…
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
GL Johnson, R Lapadat - Science, 2002 - science.org
… The c-Jun amino-terminal kinases (JNKs) are critical regulators of transcription, and JNK
inhibitors may be effective in control of rheumatoid arthritis. The p38 MAPKs are activated by …
inhibitors may be effective in control of rheumatoid arthritis. The p38 MAPKs are activated by …
[HTML][HTML] Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells
A Mansouri, LD Ridgway, AL Korapati, Q Zhang… - Journal of Biological …, 2003 - ASBMB
… of the JNK/p38 MAPK pathways by … JNK > c-Jun > FasL > Fas pathway plays an important
role in mediating cisplatin-induced apoptosis in ovarian cancer cells, and the duration of JNK …
role in mediating cisplatin-induced apoptosis in ovarian cancer cells, and the duration of JNK …
Mixed-lineage kinase control of JNK and p38 MAPK pathways
KA Gallo, GL Johnson - Nature reviews Molecular cell biology, 2002 - nature.com
… All the MLK family members have been shown to activate the JNK pathway. MLK3 and dual-…
the p38 MAPK pathway, but it is not known whether other MLKs can also activate p38. The …
the p38 MAPK pathway, but it is not known whether other MLKs can also activate p38. The …
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