Ischemic Preconditioning: From Adenosine Receptor to KATP Channel
MV Cohen, CP Baines… - Annual review of …, 2000 - annualreviews.org
… and the cell’s phospholipases induces thetranslocation and activation of the ε isozyme of
protein kinase C. Protein kinase C appears to be the first element of a complex kinase …
protein kinase C. Protein kinase C appears to be the first element of a complex kinase …
Direct activation of mitochondrial KATP channels mimics preconditioning but protein kinase C activation is less effective in middle-aged rat hearts
M Tani, Y Honma, H Hasegawa… - Cardiovascular …, 2001 - academic.oup.com
… K ATP channels mimics preconditioning but protein kinase C … of protein kinase C (PKC)
activation and, if so, whether direct activation of mitochondrial ATP-sensitive potassium channels …
activation and, if so, whether direct activation of mitochondrial ATP-sensitive potassium channels …
Role of Protein Kinase C in Mitochondrial KATP Channel–Mediated Protection Against Ca2+ Overload Injury in Rat Myocardium
… MitoK ATP channel is mainly … K ATP channel from cardiac mitochondria is 2000 times more
sensitive to diazoxide than the sarcolemmal channel, which indicates that 2 distinct channel …
sensitive to diazoxide than the sarcolemmal channel, which indicates that 2 distinct channel …
AMP-activated protein kinase connects cellular energy metabolism to KATP channel function
H Yoshida, L Bao, E Kefaloyianni, E Taskin… - Journal of Molecular and …, 2012 - Elsevier
… protein kinase (AMPK) activity promotes K ATP channel opening. ► AMPK physically interacts
with K ATP channel … Thus, small changes in AMP may trigger K ATP channel availability …
with K ATP channel … Thus, small changes in AMP may trigger K ATP channel availability …
Infarct size limitation by nicorandil: Roles of mitochondrial KATP channels, sarcolemmal KATP channels, and protein kinase C
A Tsuchida, T Miura, M Tanno, J Sakamoto… - Journal of the American …, 2002 - jacc.org
… ATP channels. Both of these K ATP channels are regulated by PKC, and this kinase may be
… oxide and also by oxygen free radicals (OFR) generated after mitoK ATP channel opening. …
… oxide and also by oxygen free radicals (OFR) generated after mitoK ATP channel opening. …
Molecular basis of protein kinase C-induced activation of ATP-sensitive potassium channels
… channels that are inhibited by internal ATP (K ATP channels) … Protein kinase C (PKC) acts
on K ATP channels to regulate … of ATP binding to cardiac K ATP channels, thereby increasing …
on K ATP channels to regulate … of ATP binding to cardiac K ATP channels, thereby increasing …
Activation of Mitochondrial KATP Channel Elicits Late Preconditioning Against Myocardial Infarction via Protein Kinase C Signaling Pathway
… K ATP (mitoK ATP ) channel induces acute ischemic preconditioning (PC) against ischemic
injury. The ability of this channel … mitoK ATP channel induces late PC via the protein kinase C …
injury. The ability of this channel … mitoK ATP channel induces late PC via the protein kinase C …
Downregulation of Protein Kinase C Inhibits Activation of Mitochondrial KATP Channels by Diazoxide
… Recently we reported that activation of mitochondrial K ATP (mitoK ATP ) channels elicits
cardiac protection against ischemia via protein kinase C (PKC) signaling pathways. In that study…
cardiac protection against ischemia via protein kinase C (PKC) signaling pathways. In that study…
Signal Transduction in Ischemic Preconditioning: The Role of KATP and Mitochondrial KATP Channels
CP Baines, MV Cohen… - Journal of cardiovascular …, 1999 - Wiley Online Library
… The stimulation of these stress-activated protein kinases ultimately induces the opening
of mitochondrial K^^p channels that may be the final mediator of protection by ischemic …
of mitochondrial K^^p channels that may be the final mediator of protection by ischemic …
[HTML][HTML] ATP-sensitive potassium channel traffic regulation by adenosine and protein kinase C
K Hu, CS Huang, YN Jan, LY Jan - Neuron, 2003 - cell.com
… To examine whether PMA affects the K ATP channel number, we quantified surface K ATP
channel proteins with the hemagglutinin (HA) epitope inserted in an extracellular loop of Kir6.2…
channel proteins with the hemagglutinin (HA) epitope inserted in an extracellular loop of Kir6.2…
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