[HTML][HTML] Role of the tumor microenvironment in tumor progression and the clinical applications

Y Yuan, YC Jiang, CK Sun… - Oncology reports, 2016 - spandidos-publications.com
tumor cells recruit stromal cells to the primary tumor site and build the microenvironment.
Moreover, we will highlight the role of the tumor microenvironment in the regulation of tumor

Tumor microenvironment

B Arneth - Medicina, 2019 - mdpi.com
… cells in the tumor microenvironment play critical roles in all … the concept of the tumor
microenvironment by conducting a … , which play a key role in tumor development and tumor cell …

[HTML][HTML] Role of tumor microenvironment in tumorigenesis

M Wang, J Zhao, L Zhang, F Wei, Y Lian, Y Wu… - Journal of …, 2017 - ncbi.nlm.nih.gov
… The tumor microenvironment and characteristics of cancer. It is currently widely recognized
that tumor microenvironments are wildly influenced by the ten main characteristics of cancer: …

The tumor microenvironment

NM Anderson, MC Simon - Current Biology, 2020 - cell.com
role of immune cells in the tumor microenvironment can be to either suppress tumor formation
(anti-tumor microenvironment… plays a key role in promoting tumor cell dissemination. Solid …

Tumor microenvironment: a metabolic player that shapes the immune response

S Cassim, J Pouyssegur - International journal of molecular sciences, 2019 - mdpi.com
… Another example of a key role of a mutation-driven metabolic rewiring that favors
tumorigenicity is oncometabolites [12]. For example, in human cancers, a consequence of gain-of-…

The role of microenvironment in tumor angiogenesis

X Jiang, J Wang, X Deng, F Xiong, S Zhang… - Journal of Experimental …, 2020 - Springer
tumor microenvironment can regulate tumor development. In this review, we have discussed
the regulatory role of the microenvironment in tumor … in HIFα is the key factor for VHL binding…

Cancer and the tumor microenvironment: a review of an essential relationship

F Mbeunkui, DJ Johann - Cancer chemotherapy and pharmacology, 2009 - Springer
… Secreted proteins are of particular importance because they play a key role in a disease
state or the biological pathway leading to disease, and their identification and characterization …

Role of the tumor microenvironment in breast cancer

SD Soysal, A Tzankov, SE Muenst - Pathobiology, 2015 - karger.com
… alterations in the surrounding stroma or tumor microenvironment. These alterations are
now … are emerging as one of the key players in the tumor microenvironment. The majority of …

Tumor-intrinsic signaling pathways: key roles in the regulation of the immunosuppressive tumor microenvironment

L Yang, A Li, Q Lei, Y Zhang - Journal of hematology & oncology, 2019 - Springer
tumor-intrinsic signaling plays a key role in regulating the immunosuppressive tumor
microenvironment and tumor … immune avoidance mediated by tumor-intrinsic signaling may help …

The role of the tumor microenvironment in regulating angiogenesis

RS Watnick - Cold Spring Harbor perspectives in …, 2012 - perspectivesinmedicine.cshlp.org
… the keytumor-associated stroma, or tumor microenvironment, can grossly be categorized
into two types of cells: (1) cells that are present in the normal tissue parenchyma before tumor