Chronic kidney disease and exposure to nephrotoxic metals

SE Orr, CC Bridges - International journal of molecular sciences, 2017 - mdpi.com
… the uptake of Cd ions [113,123,124,125,126]. Both of these carriers have been identified in
the kidney [127] and appear to play important roles in the accumulation of Cd ions in proximal …

Trace elements in patients with chronic kidney disease

A Davenport - Chronic renal disease, 2015 - Elsevier
… Accidental intoxications usually result in gastrointestinal absorption, with the majority of the
divalent metal ions absorbed binding to circulating plasma proteins, predominantly albumin, …

Chronic kidney disease of unknown etiology and the effect of multiple-ion interactions

MWC Dharma-Wardana - Environmental geochemistry and health, 2018 - Springer
kidney disease that has reached epidemic proportions in the North Central Province of Sri
Lanka as being most likely due to the joint presence of fluoride and magnesium ionsmetals: …

Exploring the root cause for chronic kidney disease of unknown etiology (CKDU) via analysis of metal ion and counterion contaminants in drinking water: A study in Sri …

W Perera, M Dayananda, JA Liyanage - Journal of Chemistry, 2020 - Wiley Online Library
… is responsible for entering nephrotoxic ion contaminants into the human body. … kidney tissue
damage due to long-term exposure to drinking water with elevated levels of some metal ions

The role of ions, heavy metals, fluoride, and agrochemicals: critical evaluation of potential aetiological factors of chronic kidney disease of multifactorial origin …

SJ Wimalawansa - Environmental geochemistry and health, 2016 - Springer
… contaminated with heavy metals, fluoride, and other toxins causes insidious illnesses that
lead to protracted, non-communicable diseases and death. Chronic kidney disease of unusual/…

Role of toxic elements in chronic kidney disease

A Fevrier-Paul, AK Soyibo… - Journal of Health …, 2018 - meridian.allenpress.com
disease and mineral bone disorder rank as the most common complications of severe kidney
disease. … In addition, ZIP-8, a metal-ion transporter like DMT-1, non-selectively binds other …

Associations among heavy metals and proteinuria and chronic kidney disease

HJ Tsai, CH Hung, CW Wang, HP Tu, CH Li, CC Tsai… - Diagnostics, 2021 - mdpi.com
kidney disease (CKD) is increasing annually in Taiwan. In addition to traditional risk factors,
heavy metals … The aim of this study was to investigate associations among heavy metals and …

The divalent elements changes in early stages of chronic kidney disease

WJ Kung, CT Shih, CH Lee, CC Lin - Biological trace element research, 2018 - Springer
… , especially in the divalent metal ions, such as magnesium… metal transporter 1 (DMT1).
Competition between divalent cations can lead to failure to reabsorb the essential divalent metals

Molecular mechanisms of cellular injury and role of toxic heavy metals in chronic kidney disease

M Mishra, L Nichols, AA Dave, EH Pittman… - International Journal of …, 2022 - mdpi.com
… Chronic kidney disease (CKD) is a progressive disease that affects millions of adults every
year. Major risk factors include diabetes, hypertension, and obesity, which affect millions of …

Heavy Metal Intoxication: A Key-Player in Chronic Kidney Disease (A Review)

O Ibama - Asian Journal of Research in Biochemistry, 2019 - article.researchpromo.com
… During acute heavy metal intoxication, the heavy metal ions bind rapidly to albumin (at
the free sulfhydryl group of terminal cysteine and histidine residues) in the plasma [27], with …