… in renal diseases. In this chapter, we discuss evidence supporting mitochondrial
dysfunction in the pathogenesis of kidney disease, and summarize the recent development of …

… of mitochondrial ROS is associated with mitochondrial … damage and progression of kidney
disease. We and others have identified enhanced mitochondrial ROS in vitro and in kidneys of …

… kidney cells could be of great significance to prevent and control the progression of this
disease… of oxidative stress damage and mitochondrial dysfunction in kidney disease. In this …

… Evidence from preclinical models suggests that mitochondrial damage in diabetes can be …
role of mitochondria in kidney function and discuss the role of mitochondrial dysfunction in the …

… stress in the kidneys based in their mitochondria-targeted effects. This … of kidney diseases
by modulating mitochondrial function. … severe mitochondrial damage; however, mitochondrial …

… kidney disease. We discuss the processes that control mitochondrial stress responses to kidney
… , we reported evidence of mitochondrial damage, with mitochondrial swelling and loss of …

… kidney disease is limited by our poor mechanistic understanding of disease pathogenesis. …
Damaged mitochondria fail to supply sufficient ATP, causing an energetic deficit, resulting in …

… blood flow, include direct damage to the kidneys and blockage of the urinary tract [3]. Chronic
kidney disease (CKD) is defined as the presence of kidney damage persisting over a long …

… Cellular metabolic changes during chronic kidney disease (… damage and in the onset of
important comorbidities. This condition seems to be in part related to dysfunctional mitochondria …

… and mitochondrial damage has a role in the pathophysiology of acute kidney injury (AKI) …
in their second or third decade of life and chronic kidney disease was present in half of these …