… Mitochondrial dysfunction is associated with kidney disease in nondiabetic contexts, and
increasing evidence suggests that dysfunctional renal mitochondria … mitochondrial dysfunction …

… Although it has become increasingly clear that mitochondrial dysfunction is … of kidney
diseases leading to CKD (Figure 4), our understanding of the impact of mitochondrial dysfunction in …

… Our understanding on mitochondrial dysfunction in kidney disease has dramatically
increased in the past decade. However, there are several challenges to researchers in this area. …

… that circulating biomarkers of mitochondrial dysfunction and oxidative stress increase with
the severity of chronic kidney disease. We found that mitochondrial dysfunction, measured by …

… chronic kidney disease. We organized the causes and risk factors of oxidative stress in the
kidneys based in their mitochondria-… of kidney diseases by modulating mitochondrial function. …

… can further exaggerate kidney injury. This review provides a comprehensive overview of
the role of mitochondrial dysfunction in acute kidney injury and chronic kidney disease. We …

… are linked to mitochondrial metabolism and … of mitochondrial activity in diabetic kidney
disease. Supporting this analysis, human diabetic kidney sections expressed less mitochondrial …

… Thus mitochondrial dysfunction plays a critical role in the pathogenesis of kidney diseases.
To illuminate the involvement of mitochondrial dysfunction in kidney diseases, we first review …

… This review covers the potential contribution of mitochondrial dysfunction to the pathophysiology
of kidney disease and reviews significant progress in mitochondria-targeted treatments. …

… kidney disease is limited by our poor mechanistic understanding of disease pathogenesis. …
dysfunction, death pathways playing role in kidney disease are discussed in this Review. …