Role of FGF23 in vitamin D and phosphate metabolism: implications in chronic kidney disease

LD Quarles - Experimental cell research, 2012 - Elsevier
… for the variable effects of phosphate in regulating FGF23? Serum phosphate levels positively
correlate with elevations in FGF23 levels in ESRD [97], but phosphate restriction failed to …

[HTML][HTML] Phosphate and kidney healthy aging

I Rubio-Aliaga - Kidney and Blood Pressure Research, 2020 - karger.com
phosphate intake is rare but can cause acute kidney injury. Yet, the question if controlling
phosphate intake may modulate serum phosphate … truly suffer from kidney disease? Do they …

Phosphate, fibroblast growth factor 23 and retinopathy in chronic kidney disease: the Chronic Renal Insufficiency Cohort Study

R Mehta, GS Ying, S Houston, T Isakova… - Nephrology Dialysis …, 2015 - academic.oup.com
… microvascular disease in the kidney [18]. Previously, we showed that higher serum phosphate
… In this study, we tested the hypothesis that higher serum phosphate is similarly associated …

The challenge of controlling phosphorus in chronic kidney disease

JB Cannata-Andía, KJ Martin - Nephrology Dialysis …, 2016 - academic.oup.com
… Recently, the COSMOS European study conducted in CKD 5 patients suggested 3.6–5.2
mg/dL as the safest serum phosphate range—values based on the serum phosphorus levels in …

Klotho, phosphate and inflammation/ageing in chronic kidney disease

MC Izquierdo, MV Perez-Gomez… - Nephrology Dialysis …, 2012 - academic.oup.com
serum phosphate was independently associated with inflammatory markers such as interleukin
(IL)-6 and it was hypothesized that elevated serum phosphate … between CKD, phosphate, …

Bone metabolism and disease in chronic kidney disease

G Eknoyan, A Levin, NW Levin - American Journal of Kidney Diseases, 2003 - ajkd.org
disease have their onset in the early stages of CKD, continue throughout the course of
progressive loss of kidney … early in the course of chronic kidney disease are extremely important in …

[HTML][HTML] Clinical relevance of FGF-23 in chronic kidney disease

S Seiler, GH Heine, D Fliser - Kidney International, 2009 - Elsevier
phosphate excretion in order to maintain serum phosphate levels within the normal range.
In patients with chronic kidney disease (… increase in serum phosphate concentration can be …

The pathophysiology of early‐stage chronic kidney disease–mineral bone disorder (CKD‐MBD) and response to phosphate binders in the rat

SM Moe, JS Radcliffe, KE White… - Journal of Bone and …, 2011 - academic.oup.com
… We used the Cy/+ rat, a Han:SPRD rat with autosomal dominant polycystic kidney disease.9
The male Cy/+ rat develops a slowly progressive azotemia accompanied by spontaneous …

[HTML][HTML] Hyperphosphatemia management in patients with chronic kidney disease

AM Shaman, SR Kowalski - Saudi Pharmaceutical Journal, 2016 - Elsevier
… If the skeletal system does not accommodate the increased serum phosphate concentration,
serum phosphate can interact with calcium to precipitate calcium phosphate salts (…

EARLY INITIATION OF PHOSPHATE LOWERING DIETARY THERAPY IN NON‐DIALYSIS CHRONIC KIDNEY DISEASE: A CRITICAL REVIEW

MK Sigrist, G Chiarelli, L Lim, A Levin - Journal of renal care, 2009 - Wiley Online Library
… This review will discuss the complications associated with higher serum phosphate, the
potential benefits of early phosphate intervention, practical considerations of low …