… Primary tubular diseases generally display as acute kidney injury (AKI or acute renal failure),
in which the majority of affected tubules undergoes complete regeneration [6]. However, in …

… explanation of macrophage accumulation after kidney injury. In addition, dynamic Ly6C …
in handling kidney inflammation and fibrosis. Mechanisms underlying kidney macrophage …

… in knowing the mechanism of renal fibrosis to detailed cellular … fibrosis. Research and
clinical trial are underway for emerging biomarkers detecting early kidney injury, predicting kidney …

… , injured proximal tubule epithelial cells are still considered important drivers of kidney injury
and fibrosis, … -seq studies in mouse models of acute kidney injury (21, 22). snRNA-seq in a …

… Kidney fibrosis could be a consequence of kidney injury and inflammation, … kidney injury
and inflammation respectively, to impact indirectly or directly on the degree of kidney fibrosis (…

Acute kidney injury (AKI) is a renal disease with a high incidence and mortality. Currently,
there are no targeted therapeutics for preventing and treating AKI. Macrophages, important …

… of kidney injury into humans. Nevertheless, our main finding that focal IF/TA and diffuse
fibrosis are independent patterns of kidney fibrosis in ANCA GN (and other chronic kidney …

… kidney transplants who had developed a fibrotic CKD of their transplant and collected biopsies
from normal healthy kidneys … comparing fibrotic kidney miR levels with normal kidney miR …

… cells into sites of injury. In this study, we investigated the role of CXCL16 in renal injury and
fibrosis in Ang II–induced hypertensive kidney disease using CXCL16 knockout (KO) mice. …

… therapy in acute and chronic kidney injury models, we have recently reported that resident
perivascular MSCs are an important source of myofibroblasts driving kidney fibrosis [1] . …