Delivering drugs to tubular cells and organelles: the application of nanodrugs in acute kidney injury

Z Li, X Fan, J Fan, W Zhang, J Liu, B Liu, H Zhang - Nanomedicine, 2023 - Taylor & Francis
Acute kidney injury (AKI) is a common clinical syndrome with limited treatment options and
high mortality rates. Proximal tubular epithelial cells (PTECs) play a key role in AKI …

[HTML][HTML] Nanodrugs alleviate acute kidney injury: Manipulate RONS at kidney

Q Chen, Y Nan, Y Yang, Z Xiao, M Liu, J Huang… - Bioactive materials, 2023 - Elsevier
… emerging nanodrugs that exploit the pathological and physiological features of the kidney to
… used to improve renal targeting and reviewed advances of nanodrugs for AKI: nano-RONS-…

Engineered nanodrug targeting oxidative stress for treatment of acute kidney injury

L Li, Y Shen, Z Tang, Y Yang, Z Fu, D Ni, X Cai - Exploration, 2023 - Wiley Online Library
nanodrugs passively or actively targeting the glomerular filtration barrier (GFB) in AKI
treatments. Then, engineered nanodrugs … for the clinical application of engineered nanodrugs for …

Renal Nano-drug delivery for acute kidney Injury: Current status and future perspectives

HN Geo, DD Murugan, Z Chik, A Norazit, YY Foo… - Journal of Controlled …, 2022 - Elsevier
… and future trajectories of renal nanomedicine research for AKI … We then introduce the
application of NDCs in renal drug … Lastly, we critically review the application of NDCs to the in vivo …

Nanotechnology-Based Drug Delivery Systems for Treating Acute Kidney Injury

W Qin, J Huang, M Zhang, M Xu, J He… - … Biomaterials Science & …, 2024 - ACS Publications
… We then summarize the application of nanomedicine in AKI … how to realize the application
of nanomedicine in the treatment … Finally, we also discuss the application of nanomedicines to …

Application of nanotechnology in acute kidney injury: From diagnosis to therapeutic implications

Y Zhao, M Pu, Y Wang, L Yu, X Song, Z He - Journal of Controlled Release, 2021 - Elsevier
nanomedicines in the applicationkidney repair or recovery from AKI. The review provides
insights into the synthesis, advantages, and limitations of innovative nanomedicine application

Recent Advances in Nanomaterials for the Treatment of Acute Kidney Injury

X Ba, T Ye, H Shang, Y Tong, Q Huang… - … Applied Materials & …, 2024 - ACS Publications
… Up to now, no nanomedicine products have obtained the clinical use approval for AKI …
clinical application of these nanomedicines on patients. The action mechanism of nanomedicine

[HTML][HTML] Recent advances in nanotherapeutics for the treatment and prevention of acute kidney injury

H Yu, D Liu, G Shu, F Jin, Y Du - Asian Journal of Pharmaceutical Sciences, 2021 - Elsevier
… Acute kidney injury (AKI) is a serious kidney disease without specific … Besides, kidney-targeted
drugs are not common and small … We will discuss the application of active targeting in AKI …

[HTML][HTML] Targeted therapy of kidney disease with nanoparticle drug delivery materials

S Shang, X Li, H Wang, Y Zhou, K Pang, P Li, X Liu… - Bioactive Materials, 2024 - Elsevier
kidney function protection and recovery after injury complex. This also lays the foundation for
the application of nanomedicine in kidney … of kidney injury during acute kidney injury (AKI) …

[HTML][HTML] Nanotherapeutic kidney cell-specific targeting to ameliorate acute kidney injury

Y Funahashi, SH Park, JF Hebert, MB Eiwaz… - Kidney International, 2024 - Elsevier
… Acute kidney injury complicates severe illness and can lead to death or chronic kidney … the
complex environment of care around acute kidney injury. These data support the rodent and …