… injury, promoting the idea that the major impact of cell-based therapy for acute kidney
injury may result from paracrine or endocrine effects unrelated to stem cell transdifferentiation. …

… The tubular epithelium of the kidney is susceptible to injury … kidney injury, which may progress
to chronic kidney disease and fibrosis. Acute kidney injury involves not only direct injury to …

… cell survival, proliferation, growth and changes in cellular … as the main reason for poor cell
survival rate. Genetic modification to make … improved their survival rate in injured tissues.46, 47 …

… Collectively, our data suggest that after kidney injury Hh signaling has a complex role in
initiating both reparative and proproliferative and survival signaling in tubular epithelial cells. …

… Together, these observations show that the balance between pro- and anti-apoptotic growth
factors is an important determinant of renal epithelial cell survival and kidney function post-…

… tubular epithelial cells are the primary targets of kidney injury, but viable tubular cells may
undergo dedifferentiation, migration, and proliferation to replace dead tubular cells after injury.…

… the attenuation of protein translation, to maintain ER homeostasis and ensure cell survival.
In tubules, apoptosis resulting from epithelial cell damage is caused, at least in part, by the …

… Bcl-2 gene family cell death or survival genes? The growth factors … a correlation between
cell survival promoted by members of … in cell populations protected by the anti-apoptotic genes. …

… interventions reliably improve survival, limit injury, or speed … kidney disease (CKD), is rich
with biological targets. We review recent findings relating to the renal vasculature and cellular …

… of renal tissue injury and tubular cell apoptosis and to … , improved survival, and prevent tissue
and organ injuries in … involved in cell signaling pathways, such as apoptosis or cell survival. …