[HTML][HTML] Molecular characterization of the transition from acute to chronic kidney injury following ischemia/reperfusion
… injury/repair, fibrosis, and innate and adaptive immunity. Intersection of these data with
human kidney transplant expression profiles identified overlapping gene expression signatures …
human kidney transplant expression profiles identified overlapping gene expression signatures …
Comparison of acute kidney injury of different etiology reveals in-common mechanisms of tissue damage
M Hultström, M Becirovic-Agic… - Physiological …, 2018 - journals.physiology.org
… This tissue damage can cause tubular atrophy and interstitial fibrosis that leads to … kidney
disease (CKD). This review describes the in-common mechanisms behind tissue damage in …
disease (CKD). This review describes the in-common mechanisms behind tissue damage in …
[HTML][HTML] Identification of common molecular signatures of SARS-CoV-2 infection and its influence on acute kidney injury and chronic kidney disease
W Zhang, L Liu, X Xiao, H Zhou, Z Peng… - Frontiers in …, 2023 - frontiersin.org
… Acute kidney injury (AKI) is a common complication of COVID-19 … kidney disease (CKD)
is a high risk factor for COVID-19 and its related mortality. However, the underlying molecular …
is a high risk factor for COVID-19 and its related mortality. However, the underlying molecular …
[HTML][HTML] Identification of novel key molecular signatures in the pathogenesis of experimental diabetic kidney disease
M Diao, Y Wu, J Yang, C Liu, J Xu, H Jin… - Frontiers in …, 2022 - frontiersin.org
… This study aimed to identify critical molecular signatures and … kidney disease (T1DKD) and
type 2 diabetic kidney disease (… These identified novel molecular signatures in DKD merit …
type 2 diabetic kidney disease (… These identified novel molecular signatures in DKD merit …
Molecular signatures of diabetic kidney disease hiding in a patient with hypertension-related kidney disease: a clinical pathologic molecular correlation
J Patel, JR Torrealba, ED Poggio… - Clinical Journal of the …, 2022 - journals.lww.com
… molecular analysis added a new dimension of understanding to the pathophysiology of
kidney disease … important mechanisms of adaption and injury related to diabetes mellitus that …
kidney disease … important mechanisms of adaption and injury related to diabetes mellitus that …
[HTML][HTML] Transcriptional trajectories of human kidney injury progression
… Among the major communities identified with this approach, community A presented a
transcriptional signature related to kidney injury, fibrosis, and chronic inflammation (Figures 3, A …
transcriptional signature related to kidney injury, fibrosis, and chronic inflammation (Figures 3, A …
Defining the acute kidney injury and repair transcriptome
S Kumar, J Liu, AP McMahon - Seminars in nephrology, 2014 - Elsevier
… Recently, a generalized TRAP approach was developed and applied to the mouse kidney
to obtain cell-specific molecular signatures in an IRI-invoked AKI model. Here, TRAP relies on …
to obtain cell-specific molecular signatures in an IRI-invoked AKI model. Here, TRAP relies on …
[HTML][HTML] Altered molecular signatures during kidney development after intrauterine growth restriction of different origins
E Nüsken, G Fink, F Lechner, J Voggel… - Journal of Molecular …, 2020 - Springer
… To rule out acute severe kidney damage by our experimental setting, we performed western
blots of proteins indicative of cellular stress, autophagy, and apoptosis (CHOP, LC3BI/LC3BII…
blots of proteins indicative of cellular stress, autophagy, and apoptosis (CHOP, LC3BI/LC3BII…
Molecular and clinical signatures in Acute Kidney Injury define distinct subphenotypes that associate with death, kidney, and cardiovascular events
… Biomarkers reflective of key biological pathways such as kidney injury, inflammation, and …
of acute kidney injury (AKI) and forecast adverse outcomes in this population including disease …
of acute kidney injury (AKI) and forecast adverse outcomes in this population including disease …
[HTML][HTML] Cell-specific translational profiling in acute kidney injury
J Liu, AM Krautzberger, SH Sui… - The Journal of …, 2014 - Am Soc Clin Investig
… A driver for development of TRAP technology has been the need to obtain molecular
signatures for adult neuronal types where recovery of intact cells is not possible through tissue …
signatures for adult neuronal types where recovery of intact cells is not possible through tissue …
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