Pathophysiological role of different tubular epithelial cell death modes in acute kidney injury

SM Sancho-Martínez, JM López-Novoa… - Clinical kidney …, 2015 - academic.oup.com
cell death and we also critically review the existing evidence on the occurrence of different
types of cell … We also discuss the pathophysiological mechanisms linking tubule epithelial cell

Kidney injury molecule‐1: More than just an injury marker of tubular epithelial cells?

AI Lim, SCW Tang, KN Lai… - Journal of cellular …, 2013 - Wiley Online Library
injury, in which the proximal tubular epithelial cells (PTEC) are instrumental. Kidney injury
… upon injury. KIM-1 plays the role as a double-edged sword and implicates in the process of …

Epithelial cell states associated with kidney and allograft injury

C Hinze, S Lovric, PF Halloran, J Barasch… - Nature Reviews …, 2024 - nature.com
… acute kidney injury (AKI) have identified the emergence of distinct epithelial cell states following
injury (… An unknown population of injured, dedifferentiated epithelial cells undergoes cell

[PDF][PDF] Intrinsic epithelial cells repair the kidney after injury

BD Humphreys, MT Valerius, A Kobayashi, JW Mugford… - Cell stem cell, 2008 - cell.com
epithelial cells expressed RFP after one cycle of injury and repair and 94.1% ± 2.0% expressed
RFP after two cycles of injury and … at baseline and at 2, 7, or 15 days after kidney injury. …

[HTML][HTML] Mechanisms of epithelial repair and regeneration after acute kidney injury

K Berger, MJ Moeller - Seminars in nephrology, 2014 - Elsevier
… parietal epithelial cells, proliferate more than the remaining proximal tubule cells, and are less
susceptible to injuries… and manipulated by the parietal epithelial cell–specific, doxycycline …

Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury

T Ichimura, JV Bonventre, V Bailly, H Wei… - Journal of Biological …, 1998 - ASBMB
kidney but are increased dramatically in postischemic kidney.… vimentin-positive epithelial
cells in regenerating proximal … an epithelial cell adhesion molecule up-regulated in the cells

[HTML][HTML] Alteration of fatty acid oxidation in tubular epithelial cells: from acute kidney injury to renal fibrogenesis

N Simon, A Hertig - Frontiers in medicine, 2015 - frontiersin.org
… acute kidney injury-induced renal fibrogenesis, thence to the development of chronic kidney
… affects the fate of tubular epithelial cells, by promoting epithelial-to-mesenchymal transition, …

Kidney injury molecule–1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells

T Ichimura, EJP Asseldonk… - The Journal of …, 2008 - Am Soc Clin Investig
… is an immunoglobulin superfamily cell-surface protein not expressed by cells of the myeloid
… of injured kidney epithelial cells. Here we demonstrate that injured kidney epithelial cells

Controversies on the origin of proliferating epithelial cells after kidney injury

T Kusaba, BD Humphreys - Pediatric nephrology, 2014 - Springer
… As alluded to above, we previously demonstrated that surviving tubular epithelial cells are
responsible for kidney regeneration after injury using a genetic fate-mapping technique with …

The role of metabolic reprogramming in tubular epithelial cells during the progression of acute kidney injury

Z Li, S Lu, X Li - Cellular and Molecular Life Sciences, 2021 - Springer
… , ischemia or toxic injury, primarily target the tubular epithelial cells especially the highly …
Proximal tubular cells (PTCs) are the most energy-demanding cells, which efficiently use …