… However, in many cases repair of epithelial cells does not … the migration of epithelial cells
from the neighbouring epithelia, as … epithelium can be self-renewing after acute kidney injury. …

… This review focuses on epithelial and endothelial injury mediators, interactions, and targets
… of PTC repair following severe injury. Increasing the duration of ischemia results in worse cell …

… Initial responses are likely an attempt at kidney repair and recapitulate embryologic … that
these epithelial cells have excellent regenerative capacity after mild acute kidney injuries (AKI), …

… Resident kidney epithelial cells play an important role in detection of injury, regulation of
the inflammatory and tissue repair responses, and mediation of interstitial fibrosis through …

… maladaptive epithelial repair leading to interstitial fibrosis and CKD (4, 5). To develop targeted
therapies that promote kidney repair after acute injury and prevent maladaptive repair and …

… repair after acute kidney injury. We describe a small population of proximal tubule cells that
fail to repair (FR-… an injured epithelial cell repairs successfully or not. Whether similar failed …

… acute kidney injury. Our understanding of the histopathologic course of ischemic kidney injury
… important role in stimulating repair and regeneration of renal epithelial cells after ischemic …

… of renal epithelial cells, but not non-epithelial interstitial cells, were subjected to a single cycle
or sequential cycles of kidney injury and repair. No dilution of the epithelial cell fate marker …

… kidneys can occur either abruptly (termed acute kidney injury… , but epithelial repair was
adaptive and injury was reversible. … , however, repair was maladaptive with sustained injury and …

… However, the adoptive transfer of purified B cells back into these mice does not repair
kidney injury after ischemia. On the other hand, when compared to B celldeficient mice without …