[HTML][HTML] Gene expression profiling of sepsis‑associated acute kidney injury

JJ Yang, BB Wu, F Han… - Experimental and …, 2020 - spandidos-publications.com
… to investigate gene expression profiles related to mice with SA-AKI that exhibited persistent
injury or recovery. The current study identified some prognosis-related genes, transcription …

Kidney physiology and susceptibility to acute kidney injury: implications for renoprotection

H Scholz, FJ Boivin, KM Schmidt-Ott… - Nature Reviews …, 2021 - nature.com
Kidney damage varies according to the primary insult. Different aetiologies of acute kidney
injury (AKI), including kidney … of damage and changes in gene expression, which can provide …

Uremia impacts renal inflammatory cytokine gene expression in the setting of experimental acute kidney injury

RA Zager, ACM Johnson… - American Journal of …, 2009 - journals.physiology.org
… the expression of least 69 microRNAs (P < 0.0001). We conclude that both pro- and anti-inflammatory
cytokine gene expressions … Changes in gene transcription (as reflected by Pol II …

Sex diversity in proximal tubule and endothelial gene expression in mice with ischemic acute kidney injury

JL Viñas, CJ Porter, A Douvris, M Spence… - Clinical …, 2020 - portlandpress.com
… after ischemic injury. Accordingly, the objective of the present study was to compare renal
gene expression profiles in male and female mice with kidney ischemic injury. To identify …

Biomarkers of kidney injury

A Urbschat, N Obermüller, A Haferkamp - Biomarkers, 2011 - Taylor & Francis
… In prerenal and postrenal injury, NGAL and MCP-1 gene expression increased comparably.
In contrast, uremia per se already induced the NGAL gene in the absence of renal injury, but …

Comparison of acute kidney injury of different etiology reveals in-common mechanisms of tissue damage

M Hultström, M Becirovic-Agic… - Physiological …, 2018 - journals.physiology.org
… by which different diseases cause tissue injury in AKI based on common gene expression
profiles from published surveys of renal gene expression in AKI of different etiology (Fig. 1). …

[HTML][HTML] Molecular characterization of the transition from acute to chronic kidney injury following ischemia/reperfusion

J Liu, S Kumar, E Dolzhenko, GF Alvarado, J Guo… - JCI insight, 2017 - ncbi.nlm.nih.gov
… to kidney injury and a resource for the clinical and research community. Further, individual
genes … To examine gene expression profiles in detail, we analyzed RNA-seq data at the …

MCP-1 gene activation marks acute kidney injury

R Munshi, A Johnson, ED Siew, TA Ikizler… - Journal of the …, 2011 - journals.lww.com
… Endotoxemia, ureteral obstruction, and bilateral ureteral transection affect MCP-1 and NGAL
gene expression. NGAL and MCP-1 gene expression were assessed in mouse renal cortex …

The local and systemic inflammatory transcriptome after acute kidney injury

DN Grigoryev, M Liu, HT Hassoun… - Journal of the …, 2008 - journals.lww.com
… The global gene expression profiling of injured mouse kidney … The injury severity-dependent
changes in gene expression … the SCr and kidney morphology at early (6 h after injury) and …

[HTML][HTML] Molecular differences in susceptibility of the kidney to sepsis-induced kidney injury

M Matejovic, L Valesova, J Benes, R Sykora, R Hrstka… - BMC nephrology, 2017 - Springer
… Septic acute kidney injury affects 40–50% of all septic patients. Molecular differences …
acute kidney injury (AKI) are only poorly understood. Here, we investigated gene expression