… Additionally, we provide some updated potential therapeutic targets for the prevention or …
Finally, we propose mechanisms of ischemic AKI-induced liver, intestine, and kidney …

Acute kidney injury (AKI) is a common complication in critically ill patients and subsequently
worsens outcomes. Although many drugs to prevent and treat AKI have shown benefits in …

… therapeutic … kidney injury. Confirmation that any of the drugs reviewed in this paper are
safe and effective in patients with impaired kidney function will open the way to new therapeutic …

… kidney injury, its progression to fibrosis, or both, are examined to gain mechanistic insights
and identify potential therapeutic targets for cisplatin-induced kidney … chronic kidney injuries. …

… therapies which target miRs. Since many of the candidate therapeutic targets identified to
date in kidney … or homeostasis, design of successful therapies for CKD has been held back by …

… Iron plays a key role in inducing cell death in acute kidney injury. Drugs targeting
ferroptosis and hepcidin are attractive targets to prevent and treat acute kidney injury (AKI). …

… At the same time, I/R injury is one of the major causes of acute kidney injury (AKI), causing
significant morbidity and mortality. This review highlights the current knowledge on the …

… article are all associated with potential novel therapeutic targets for the treatment of
COVID-19-associated AKI or COVID-19 in general. These targets include the steps of the viral cellular…

The current lack of complete understanding of the pathogenesis of acute kidney injury (AKI)
is a significant barrier to its early diagnosis and treatment. Cell cycle arrest plays an …

… Sepsis-associated acute kidney injury (SA-AKI) is linked to high morbidity and mortality.
To date, singular approaches to target specific pathways known to contribute to the …