… We also show that kidney injury after UUO potently induces autophagy and regulates TGF-β
expression and that deficiency of autophagic protein LC3 (microtubule-associated protein 1 …

… Acute kidney injury (AKI), contrary to CKD, is characterized by a sudden and reversible fall …
adult patients) showed that individuals with acute kidney injury (AKI) are at more elevated risk …

… These events also suggest several epithelial- and endothelial-specific therapeutic targets
that could limit microvascular dropout and loss of kidney function secondary to the fibrotic …

… kidney injury, by forming a positive feedback loop with c-Jun to aggravate inflammation and
apoptosis in septic AKI. Thus, FABP4 may be a therapeutic target … therapeutic target for septic …

… kidney, as well as summarizing the current information linking these proteins to acute kidney
injury and chronic kidney … represent novel therapeutic targets to attenuate kidney disease. …

… focuses on putative therapeutic targets among the … these targets has to take into account
the intrinsic differences between rodent models and human ATN, the current acute kidney injury …

… tissue hypoxia during septic acute kidney injury. Renal medullary … is unlikely to be a useful
therapeutic target for septic AKI. … Thus, medullary hypoxia is likely to exacerbate kidney injury …

… diseases, including acute kidney injury and chronic kidney … and pathophysiology of the
kidney and the development of agonists … therapeutic targets for the treatment of kidney diseases. …

… Further investigation in this area is essential for the application of p53 as therapeutic target
to … of AKI and kidney repair, pinpoint the potential of p53 as a therapeutic target, and present …

Purpose Acute kidney injury (AKI) is one of the most common functional injuries observed in
trauma patients. However, certain trauma medications may exacerbate renal injury. …