[HTML][HTML] MicroRNAs as Biomarkers and Therapeutic Targets for Acute Kidney Injury

K Tsuji, H Nakanoh, K Fukushima, S Kitamura, J Wada - Diagnostics, 2023 - mdpi.com
… may be potential biomarkers and therapeutic targets for AKI. In … promising biomarkers and
potential therapeutic targets for AKI, … as therapeutic targets for kidney diseases, including AKI. …

[HTML][HTML] Transcription factors as therapeutic targets in chronic kidney disease

A Hishikawa, K Hayashi, H Itoh - Molecules, 2018 - mdpi.com
… (HIF-PH), they have been a good therapeutic target to stabilize HIF. HIF-PH are nonheme …
Cobalt, a chelator of iron, has been reported to improve kidney injury in several CKD animal …

[HTML][HTML] Major signaling pathways and key mediators of macrophages in acute kidney injury

N Li, J Chen, P Wang, H Fan… - Molecular medicine …, 2021 - spandidos-publications.com
… Acute kidney injury (AKI) has become a global public health … for identifying potential therapeutic
targets. Macrophage‑sensing … identification of novel therapeutic targets for this condition. …

[HTML][HTML] MAP3K kinases and kidney injury

L Cuarental, D Sucunza-Sáenz, L Valiño-Rivas… - Nefrología (English …, 2019 - Elsevier
… clinical use may induced acute kidney injury and nephrotic syndrome. … therapeutic targets
in kidney injury, as demonstrated for some of them. However, the role of most MAP3K in kidney

Autophagy: a novel therapeutic target for kidney diseases

S Kume, T Uzu, H Maegawa, D Koya - Clinical and experimental …, 2012 - Springer
kidney lesions in some conditions and situations [30, 31]. For activation of autophagy to serve
as a therapeutic target in … protects or avoids harming the kidneys in a myriad of situations. …

Renoprotective approaches and strategies in acute kidney injury

Y Yang, M Song, Y Liu, H Liu, L Sun, Y Peng… - … & therapeutics, 2016 - Elsevier
… Acute kidney injury (AKI) is a major renal disease associated … for reducing kidney tissue
damage and promoting kidney repair … of combination therapy by targeting multiple targets in AKI. …

Acute kidney injury: emerging pharmacotherapies in current clinical trials

SW Benoit, P Devarajan - Pediatric Nephrology, 2018 - Springer
… knowledge gaps and potential new therapeutic targets of human AKI [11,12,13,14]. As
described by Basile et al., the initiation phase of kidney injury is marked by energetic failure and …

Acute kidney injury

A Zuk, JV Bonventre - Annual review of medicine, 2016 - annualreviews.org
… The connections between cellular stress responses and maladaptive repair mechanisms
are biologically complex and rich with therapeutic targets, where an impact on one can affect …

CD133+ cells as a therapeutic target for kidney diseases

B Bussolati, F Collino, G Camussi - … opinion on therapeutic targets, 2012 - Taylor & Francis
… Expert opinion: CD133 could be of interest as a possible therapeutic target for nonmalignant
renal pathology. Selective targeting of CD133 may allow pharmacological approaches to …

[HTML][HTML] Smads as therapeutic targets for chronic kidney disease

HY Lan - Kidney research and clinical practice, 2012 - Elsevier
… the exact mode of Smad4 in kidney disease remains unclear, the diverse roles for Smad4 in
renal fibrosis and inflammation suggest that Smad4 may not be a therapeutic target for CKD. …