… have their limitations as predictors of kidney injury. Thus, a sensitive and easily
detectable biomarker is needed to monitor the decline in kidney function and to separate “progressors” …

… Understanding the mechanisms and consequences of these changes may provide novel
therapeutic targets. Observed changes are dynamic in the course of injury and several …

… 21 are protected from kidney injury and fibrosis in several distinct models of kidney disease,
… may have therapeutic potential. Recent studies of microRNA-21 targets in kidney indicate …

… In this respect, it is interesting that the best biomarkers often turn out to be important in
modulation of damage and some even become therapeutic targets. The emphasis of this review is …

… biologic pathways that have suggested potential therapies for acute kidney injury (AKI) in …
hold important clues toward etiology-specific biomarkers and therapeutic targets in humans. …

… kidney injuries in order to find evidence for the role of cell death, which may pave the way
for new therapeutic … or tubulointerstitial kidney diseases [20] or as new therapeutic targets or …

… target for renal diseases. Increasing our understanding of VDR in the kidney is a fertile
area of research and may provide effective weapons in the fight against kidney diseases. …

… Renal I/R injury after hypotension due to various clinical … of acute kidney injury in both native
and transplanted kidneys. … injury, suggesting that NCX1 is a potential therapeutic target in I/…

… Of note, at the acute phase in severe kidney injury as well as chronic kidney injury, it
often occurs that epithelial cells reduced adhesion and increased migration or invasion by …

… Glomerular hypertension is one of the main factors leading to kidney injury [94]. Choline
metabolism, amino acid metabolism, energy metabolism and oxidative stress play pivotal roles …