… injured kidney. Further research in this field is imperative for the discovery of biomarkers and
promising therapeutic targets for kidney … of macrophages in kidney injury and repair. The …

… The connections between cellular stress responses and maladaptive repair mechanisms
are biologically complex and rich with therapeutic targets, where an impact on one can affect …

… Therefore, there is an urgent need to identify novel therapeutic targets for AKI treatment. The
kidney is the second largest metabolic organ in the human body with abundant mitochondria…

… Both A1R and A2R receptors are potential therapeutic targets, and both adenosine
agonists of the A2R receptors and adenosine antagonists have been proposed for potentially …

… to explore novel medications and therapeutic targets for SA-AKI. … a potential therapeutic
target for subsequent animal experiments. … AKR1B1 as a potential therapeutic target for SA-AKI. …

… revealed that inducers and downstream targets of ERS were upregulated: PPP1R15A, JUN,
and ATF3 above all. These three genes might interact with kidney injury-related pathways (…

… The goal was to identify potential new therapeutic targets for treatment of acute kidney injury
(AKI). KIM-1 mRNA was increased at 48 hours post-ischemia in the rat, more than any other …

… We review the potential role of tyrphostins in the prophylaxis and treatment of acute kidney
injury on the basis of published studies on animals, in vitro experiments and piecemeal …

… After acute kidney injury, autophagy protects tubular cells from apoptosis and promotes
cellular regeneration (as reviewed in [5]), although extended autophagy may lead to excessive …

… treatment targets based on different cell types are described. Problems that continue to
plague the field are also discussed, including specific therapeutic targeting of the kidney, the …