Origin of regenerating tubular cells after acute kidney injury

K Berger, JM Bangen, L Hammerich… - Proceedings of the …, 2014 - National Acad Sciences
… efficiently labels the scattered tubular cell population. Proximal tubular cells labeled by the
PEC–rtTA mouse coexpressed markers for scattered tubular cells (kidney injury molecule 1, …

Pathophysiological role of different tubular epithelial cell death modes in acute kidney injury

SM Sancho-Martínez, JM López-Novoa… - Clinical kidney …, 2015 - academic.oup.com
kidney injury (AKI) has been classically attributed to tubular necrosis. However, more recent
studies indicate that necrosis is not the main form of cell … ), autophagic cell death and mitotic …

Kidney injury molecule‐1: More than just an injury marker of tubular epithelial cells?

AI Lim, SCW Tang, KN Lai… - Journal of cellular …, 2013 - Wiley Online Library
tubular segments to different kinds of specific kidney injury. In rodent models of kidney ischemia
and reperfusion injury (… in midcortical and superficial tubules in proteinuria-induced renal …

[HTML][HTML] Renal tubule injury: a driving force toward chronic kidney disease

BC Liu, TT Tang, LL Lv, HY Lan - Kidney international, 2018 - Elsevier
… of glomerular injury.1, 2, 3 Maladaptive repair of injured tubules after acute kidney injury (…
heat-shock proteins released by necrotic tubular cells can activate TLR2 and TLR4 on TECs.…

Distal tubular epithelial cells of the kidney: Potential support for proximal tubular cell survival after renal injury

GC Gobe, DW Johnson - The international journal of biochemistry & cell …, 2007 - Elsevier
… The outcome is often acute kidney injury, which may progress to chronic kidney disease …
Acute kidney injury involves not only direct injury to the distal tubular (DT) and proximal tubular (…

[HTML][HTML] The pathological role of damaged organelles in renal tubular epithelial cells in the progression of acute kidney injury

Z Li, Z Liu, M Luo, X Li, H Chen, S Gong, M Zhang… - Cell Death …, 2022 - nature.com
… inhibition of mitochondrial fission alleviated tubular cell death and renal injury [14]. … from
the kidney proximal tubular cells had less severe tissue damage, fewer apoptotic cells, and …

Tubular recovery after acute kidney injury

H Fattah, V Vallon - Nephron, 2018 - karger.com
… , possibly in selected nephron regions, may provide an opportunity to improve tubular
cell energetics and facilitate tubular cell recovery with consequences for kidney outcome. …

Diverse cell populations involved in regeneration of renal tubular epithelium following acute kidney injury

A Maeshima, S Takahashi, M Nakasatomi… - Stem cells …, 2015 - Wiley Online Library
… These cells comprise polarized mature epithelial cells with the capacity to regenerate …
acute kidney injury. After the insult occurs, surviving tubular cells rapidly lose epithelial cell

… pathophysiologic mechanisms of septic acute kidney injury: role of immune suppression and renal tubular cell apoptosis in murine model of septic acute kidney injury

SY Lee, YS Lee, HM Choi, YS Ko, HY Lee… - Critical care …, 2012 - journals.lww.com
kidney injury focusing on immune responses and renal tubular cell apoptosis by providing an
on-site … comparison between septic- and ischemia/reperfusion-induced acute kidney injury. …

[HTML][HTML] Endocycle-related tubular cell hypertrophy and progenitor proliferation recover renal function after acute kidney injury

E Lazzeri, ML Angelotti, A Peired, C Conte… - Nature …, 2018 - nature.com
… Acute kidney injury (… tubular cells to dedifferentiate and replace lost cells via cell division.
Here we show by tracking individual tubular cells in conditional Pax8/Confetti mice that kidney