Defining and redefining the nephron progenitor population
C Hendry, B Rumballe, K Moritz, MH Little - Pediatric Nephrology, 2011 - Springer
… In conclusion, our understanding of the nephron progenitor population within the
developing kidney has advanced considerably. However, the intricate interplay between this …
developing kidney has advanced considerably. However, the intricate interplay between this …
Nephron progenitor cells: shifting the balance of self-renewal and differentiation
… of newly formed nephrons to regulate the formation of subsequent nephrons or the …
progenitors within the developing kidney. In this review, we will focus on the nephron progenitor …
progenitors within the developing kidney. In this review, we will focus on the nephron progenitor …
Lgr5+ ve stem/progenitor cells contribute to nephron formation during kidney development
… nephron formation within the developing kidney. Here, we document expression of the adult
stem cell marker Lgr5 in the developing kidney and assess the stem/progenitor … nephrons in …
stem cell marker Lgr5 in the developing kidney and assess the stem/progenitor … nephrons in …
Kidney nephron determination
L Oxburgh - Annual review of cell and developmental biology, 2018 - annualreviews.org
… of how the nephron progenitor cell population balances … committed to nephron progenitor
or stromal progenitor fates within the … to epithelial induction of nephron formation from the CM. …
or stromal progenitor fates within the … to epithelial induction of nephron formation from the CM. …
Single adult kidney stem/progenitor cells reconstitute three-dimensional nephron structures in vitro
S Kitamura, H Sakurai, H Makino - Stem cells, 2015 - academic.oup.com
… kidney stem/progenitor cells (KS cells), derived from the S3 segment of adult rat kidney
nephrons… We previously established kidney stem/progenitor cells (KS cells) from adult kidney in …
nephrons… We previously established kidney stem/progenitor cells (KS cells) from adult kidney in …
[HTML][HTML] The number of fetal nephron progenitor cells limits ureteric branching and adult nephron endowment
C Cebrian, N Asai, V D'Agati, F Costantini - Cell reports, 2014 - cell.com
… nephron progenitor cell number, we genetically ablated 40% of these cells, asking whether
this would limit kidney size and nephron … of progenitor cells is a limiting factor during kidney …
this would limit kidney size and nephron … of progenitor cells is a limiting factor during kidney …
A synthetic niche for nephron progenitor cells
AC Brown, SD Muthukrishnan, L Oxburgh - Developmental cell, 2015 - cell.com
… a mixture of cells with varying progenitor potential. Furthermore, … This in vitro nephron
progenitor niche will have important … kidney develops by radial addition of new nephrons that form …
progenitor niche will have important … kidney develops by radial addition of new nephrons that form …
Regulation of nephron progenitor cell lifespan and nephron endowment
AJ Perl, MP Schuh, R Kopan - Nature reviews Nephrology, 2022 - nature.com
… in susceptibility to kidney disease; however, … nephron progenitor cell exhaustion, have the
potential to inform interventions to enhance nephron endowment and improve lifelong kidney …
potential to inform interventions to enhance nephron endowment and improve lifelong kidney …
Identification of adult nephron progenitors capable of kidney regeneration in zebrafish
… These findings demonstrate that lhx1a:EGFP + aggregates contain nephron progenitors
and support our observation that multiple nephron progenitors are needed to form a nephron. …
and support our observation that multiple nephron progenitors are needed to form a nephron. …
Selective in vitro propagation of nephron progenitors derived from embryos and pluripotent stem cells
S Tanigawa, A Taguchi, N Sharma, AO Perantoni… - Cell reports, 2016 - cell.com
… Nephron progenitors in the embryonic kidney propagate while generating differentiated …
of nephron progenitors, which will be essential for dissecting the mechanisms of kidney …
of nephron progenitors, which will be essential for dissecting the mechanisms of kidney …
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