… Organogenesis generates higher-order structures containing functional subunits, … pluripotent
stem cells (PSCs) has remained challenging. In this study, we report assembly of kidney …

… We previously demonstrated that exogenous human mesenchymal stem cells (hMSC) may
… kidney organogenesis ( 7 ). In this system, hMSC were injected at the site of organogenesis …

… Kidney organoids made from pluripotent stem cells have the potential to revolutionize how
kidney … , and robust method to grow kidney organoids in bulk from human induced pluripotent …

… Therefore, we sought to ‘borrow’ this programming of a developing embryo by applying the
stem cells at the niche of organogenesis. hMSCs that expressed GDNF were microinjected at …

… , we will be closer to the generation and manipulation of multiple cell lineages in the kidney.
… a single stem cell, using LacZ gene transduction with a retrovirus into a single cell of the …

… Here, we will review distinct aspects of the available kidney organoid … on kidney organoids
derived from pluripotent stem cells and we will discuss different types of pluripotent stem cells, …

… that distinct multipotent self-renewing progenitor populations coordinate cellular differentiation
of the nephron epithelium and renal stroma during mammalian kidney organogenesis. …

… kidney organogenesis from mouse renal embryonic tissue (metanephroi). Here we provide
the first evidence that metanephroi acquired a mature phenotype upon injection into LN, and …

… Although many kidney morphogenic events are replicated in metanephric organ culture,
this culture system is nevertheless an imperfect model of normal kidney organogenesis. For …

… The differentiation of hPSCs using this protocol recapitulates the developmental process of
human kidney organogenesis. Therefore, this protocol can be used as a platform for a variety …