[HTML][HTML] Hydroxycitric acid inhibits kidney stone through crystallization regulation and reduction of hyperoxalate-induced lipotoxicity

YH Zhang, JY Xian, SJ Li, CY Li, BX Yu, Q Liang… - Journal of Functional …, 2023 - Elsevier
Kidney stone is a urinary system disease with a high incidence, and effective stone drugs …
To investigate whether HCA can inhibit calcium oxalate kidney stone formation through the …

[PDF][PDF] Clinical-grade Garcinia cambogia extract dissolves calcium oxalate crystals in Drosophila kidney stone models.

QX Fan, SQ Gong, XZ Hong, XM Feng… - European Review for …, 2020 - europeanreview.org
… models, suggesting that Garcinia cambogia extract might be a new drug for kidney stone
disease. Our data also demonstrated that hydroxycitric acid directly dissolves calcium oxalate …

Hydroxycitric acid inhibits renal calcium oxalate deposition by reducing oxidative stress and inflammation

X Liu, P Yuan, X Sun, Z Chen - Current molecular medicine, 2020 - ingentaconnect.com
… supplement whose active ingredient is hydroxycitric acid (HCA). … In recent years, hydroxycitrate
acid has been reported to … role in the formation of kidney stones. This study is to explore …

Investigation of the effect of hydroxycitric acid on urinary calcium oxalate risk factors for kidney stone formation in artificial urine: theoretical modelling and in vitro …

A Ahmed - 2020 - open.uct.ac.za
University of Cape Town Page 1 Investigation of the effect of hydroxycitric acid on urinary
calcium oxalate risk factors for kidney stone formation in artificial urine: theoretical modelling …

Hydroxycitric acid prevents hyperoxaluric-induced nephrolithiasis and oxidative stress via activation of the Nrf2/Keap1 signaling pathway

B Yang, G Wang, Y Li, T Yang, H Guo, P Li, J Li - Cell Cycle, 2023 - Taylor & Francis
… /Keap1 signaling pathway may be a potential strategy to ameliorate kidney stones. Hydroxycitric
acid (HCA) is a natural organic acid isolated from the fruit shells of Garcinia cambogia. …

Hydroxycitric acid inhibits oxalate nephropathies formation through crystallization regulation and activation of the PPARα pathway

YH Zhang, SJ Li, BX Yu, Q Liang, XY Sun - bioRxiv, 2022 - biorxiv.org
Kidney stones are one of the common urological diseases with a prevalence of 1.7-14.8%
in different countries around the world [1]. The prevalence rate for Chinese adults is 5.8% (6.5…

… , double-blind, placebo-controlled clinical trial of the use of hydroxycitric acid adjuvant to shock wave lithotripsy therapy in patients with calcium stones. Stone …

M del Carmen Cano García, RC Cobos, ÁV Bohorquez… - Urolithiasis, 2023 - Springer
… using hydroxycitric acid (HCA) like adjuvant therapy. Double blind randomized clinical trial
using hydroxycitric acid … In order to confirm the presence of kidney stones and their possible …

Kidney stone prevention: dynamic testing of edible calcium oxalate scale inhibitors

MA Kelland, MF Mady, R Lima-Eriksen - Crystal growth & design, 2018 - ACS Publications
… Polyprotic acids with only a few acid groups, such as citric acid, hydroxycitric acid, and phytic
acid, … polycarboxylic acids such as polyaspartic acid, carboxymethylinulin, and polyglutamic …

[HTML][HTML] Hydroxycitric acid inhibits ectopic calcification of renal interstitial fibroblasts by suppressing cell apoptosis

WF Liu, YH Zhang, XP Zheng, Q Zhang, J Long… - Journal of Functional …, 2024 - Elsevier
… cause of renal stone formation. Hydroxycitric acid (HCA), a derivative of citric acid, has …
favorable biosafety profile and may be used as an alternative drug to inhibit kidney stones. …

Hydroxycitrate prevents calcium oxalate crystallization and kidney injury in a nephrolithiasis rat model

B Yang, J Li, B Wang, G Wang, P Li, H Guo, Y Li… - Urolithiasis, 2022 - Springer
… In this article, we provided data on whether HCA affected kidney stones and the … of hydroxycitric
acid in the urine of the HCA group was 9.882 ± 1.93 mmol/l, while hydroxycitric acid was …