Tigecycline for Treatment of Pneumonia and Empyema Caused by Carbapenemase‐Producing Klebsiella pneumoniae

MW Daly, DJ Riddle, NA Ledeboer… - … Pharmacology and …, 2007 - Wiley Online Library
… reinforces the importance of antibiotic stewardship and strict infection control practices.
Key Words: Klebsiella pneumoniae producing carbapenemase, KPC, tigecycline, …

Regulation and role of chitotriosidase during lung infection with Klebsiella pneumoniae

L Sharma, AK Amick, S Vasudevan, SW Lee… - The Journal of …, 2018 - journals.aai.org
important roles in physiology. Their well-documented regulation in various diseases and
pathological conditions further supports their importantpharmacological inhibitor of Akt in our K. …

[HTML][HTML] Colistin: Pharmacology, drug resistance and clinical applications

P Das, K Sengupta, G Goel… - Journal of The Academy …, 2017 - journals.lww.com
pharmacology, toxicity, drug resistance, importance of therapeutic drug level monitoring and
cost of one of the most important … Colistin resistance in Klebsiella pneumoniae (CRKP) is an …

Klebsiella pneumoniae siderophores induce inflammation, bacterial dissemination, and HIF-1α stabilization during pneumonia

VI Holden, P Breen, S Houle, CM Dozois, MA Bachman - MBio, 2016 - Am Soc Microbiol
… during pneumonia. IMPORTANCE Klebsiella pneumoniae causes a wide range of bacterial
diseases, including pneumonia, urinary tract infections, and sepsis. To cause infection, K. …

Antioxidant and antibacterial study of 10 flavonoids revealed rutin as a potential antibiofilm agent in Klebsiella pneumoniae strains isolated from hospitalized patients

Z Wang, Z Ding, Z Li, Y Ding, F Jiang, J Liu - Microbial pathogenesis, 2021 - Elsevier
pneumoniae is always considered the most important pathogenic bacterium, as it poses
not … to exhibit a wide range of significant pharmacological functions, including anticancer [15], …

[HTML][HTML] Klebsiella pneumoniae infection of murine neutrophils impairs their efferocytic clearance by modulating cell death machinery

CN Jondle, K Gupta, BB Mishra, J Sharma - PLoS pathogens, 2018 - journals.plos.org
… on KPn subversion of this important protective host response are … With the use of
pharmacological enhancers and blockers in-… Our study provides important insights into pathogenic …

First penicillin-binding protein occupancy patterns of β-lactams and β-lactamase inhibitors in Klebsiella pneumoniae

DS Sutaria, B Moya, KB Green, TH Kim… - Antimicrobial agents …, 2018 - Am Soc Microbiol
… Despite β-lactams serving as the cornerstone of our therapeutic armamentarium against
Klebsiella pneumoniae , PBP binding data are missing for this pathogen. We aimed to generate …

[HTML][HTML] Plant-Origin Components: New Players to Combat Antibiotic Resistance in Klebsiella pneumoniae

VM Luna-Pineda, G Rodríguez-Martínez… - International Journal of …, 2024 - mdpi.com
… bacteraemia, liver diseases, pneumonia, urinary tract infections, and septic arthritis [38,39,40].
Furthermore, it is one of the most important opportunistic pathogens to combat during …

Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health

KE Holt, H Wertheim, RN Zadoks… - Proceedings of the …, 2015 - National Acad Sciences
… The intermediate frequency of nif in KpII is intriguing; because all our KpII isolates
originated from humans, we hypothesize that nitrogen fixing is important in environmental-source …

Lessons from an outbreak of metallo-β-lactamase-producing Klebsiella oxytoca in an intensive care unit: the importance of time at risk and combination therapy

S Vergara-Lopez, MC Dominguez, MC Conejo… - Journal of Hospital …, 2015 - Elsevier
… (CRE), mainly due to Klebsiella spp., have become a serious … first strain of multidrug-resistant
Klebsiella oxytoca (MDRKO) in … The importance of previous exposure to antibiotics is also …