Infections caused by KPC-producing Klebsiella pneumoniae: differences in therapy and mortality in a multicentre study

M Tumbarello, EM Trecarichi… - Journal of …, 2015 - academic.oup.com
Objectives Infections caused by Klebsiella pneumoniae (Kp) carbapenemase (KPC)-producing
strains of Kp have become a significant threat in recent years. To assess their outcomes …

Identification of potential flavonoid compounds as antibacterial therapeutics against Klebsiella pneumoniae infection using structure-based virtual screening and …

J Dey, SR Mahapatra, TK Raj, N Misra, M Suar - Molecular Diversity, 2023 - Springer
… Henceforth, the present study aims to illustrate the inhibitory potential of flavonoids with
varying pharmacological properties, … In spite of its clinical importance, our understanding of K. …

[HTML][HTML] Urinary tract infection with Klebsiella pneumoniae in Patients with Chronic Kidney Disease

OM Cristea, CS Avrămescu, M Bălășoiu… - Current health …, 2017 - ncbi.nlm.nih.gov
… between Klebsiella pneumoniae UTIs and CKD, by evaluating clinical and laboratory
correlations. We also assessed antibiotic susceptibility of the uropathogen. An important aim of the …

[PDF][PDF] The inhibitory effect of Punica granatum on Escherichia coli and Klebsiella pneumonia Extended spectrum β-lactamase strains

WH Alamshani, F Al-Sarraj… - Novel Research in …, 2023 - academia.edu
… on the phytochemical and pharmacological effects of P. granatum extracts on E. coli and
K… as important sources of the novel bioactive agents that have useful biological activities (Zerrifi …

… Ceftazidime-Avibactam Versus Polymyxin B and Risk Factors Affecting Clinical Outcomes in Patients With Carbapenem-Resistant Klebsiella pneumoniae Infections a …

J Fang, H Li, M Zhang, G Shi, M Liu, Y Wang… - … in Pharmacology, 2021 - frontiersin.org
Background: The worldwide outbreak of carbapenem-resistant Klebsiella pneumoniae (CRKP)
has become an urgent public health problem. High mortality and lack of effective …

Klebsiella pneumoniae and type 3 fimbriae: nosocomial infection, regulation and biofilm formation

CN Murphy, S Clegg - Future microbiology, 2012 - Future Medicine
… The Gram-negative opportunistic pathogen Klebsiella pneumoniae is responsible for …
Biofilm formation on these devices is important in the pathogenesis of these bacteria, and in …

… Genomics, Molecular Docking and Molecular Dynamics Simulation Revealed LpxC as a Potential Drug Target Against Multi-Drug Resistant Klebsiella pneumoniae

S Ahmad, A Navid, AS Akhtar, SS Azam… - Interdisciplinary …, 2019 - Springer
… of pharmacologically important proteins in both docked and undocked systems [20]. Some
LpxC proteins exhibit inherently variable structural conformations, whereas other orthologous …

Inhaled fluticasone propionate impairs pulmonary clearance of Klebsiella Pneumoniae in mice

CM Patterson, RL Morrison, A D'Souza, XS Teng… - Respiratory …, 2012 - Springer
pneumonia pathogen. We chose a murine model of pulmonary infection with Klebsiella
pneumoniae … Our current study has important limitations. First, this is an animal study using a well-…

Characteristics of bacteremia between community-acquired and nosocomial Klebsiella pneumoniae infection: risk factor for mortality and the impact of capsular …

RW Tsay, LK Siu, CP Fung… - Archives of internal …, 2002 - jamanetwork.com
Klebsiella pneumoniae bacteremia is a very important cause of morbidity and mortality in
gram-negative bacteremia in Taiwan, and this is similar to the situation in most medically well-…

Structure and function relationship of OqxB efflux pump from Klebsiella pneumoniae

N Bharatham, P Bhowmik, M Aoki, U Okada… - Nature …, 2021 - nature.com
… to the antibiotic resistance in Klebsiella pneumoniae. OqxB underwent horizontal gene …
structure and important residues of OqxB (A), AcrB (B), and MexB (C). Important hydrophobic …