Effects of galanin receptor 2 and receptor 3 knockout in mouse models of acute seizures

M Drexel, F Sternberg, B Kofler, G Sperk - Epilepsia, 2018 - Wiley Online Library
… Fisher's exact test was used for analysis of the effect of threshold dose PTZ in galanin
receptor KO mice and WT littermates. One-way analysis of variance (ANOVA) with Bonferroni's …

Feeding behaviour in galanin knockout mice supports a role of galanin in fat intake and preference

AC Adams, JC Clapham, D Wynick… - Journal of …, 2008 - Wiley Online Library
… saline-treated GKO group compared to galanin-treated GKO animals (0.32 … galanin specifically
regulates fat intake, and implies that an antagonist to one or more of the galanin receptor

Galanin and galanin receptors in epilepsy

AM Mazarati - Neuropeptides, 2004 - Elsevier
galanin receptor agonists with anticonvulsant properties. We also address recently established
functions of galanin … more severe seizures in galanin peptide knockout mice, compared to …

[125I]-Galanin binding in brain of wildtype, and galanin-and GalR1-knockout mice: strain and species differences in GalR1 density and distribution

SRF Jungnickel, AL Gundlach - Neuroscience, 2005 - Elsevier
… [ 125 I]-galanin (GAL) binding sites in brain of the common C57BL/6J and 129OlaHsd mouse
strains, as well as in GAL and galanin receptor-1 (GalR1) knockout (KO) mice. In C57BL/6J …

Galanin and spinal nociceptive mechanisms: recent results from transgenic and knock-out models

Z Wiesenfeld-Hallin, XJ Xu, JN Crawley, T Hökfelt - Neuropeptides, 2005 - Elsevier
… Genetically modified mice with transgenic overexpression of galanin or depletion of genes
for galanin or galanin receptors have become available, providing a new approach for …

Sensory neuronal phenotype in galanin receptor 2 knockout mice: focus on dorsal root ganglion neurone development and pain behaviour

TJS Shi, X Hua, X Lu, S Malkmus… - European Journal of …, 2006 - Wiley Online Library
Galanin receptor 2 null mutation-carrying mice have been difficult to generate using …
receptors. The insertion of the neo-cassette into the GalR2 intron has, however, produced a mouse

Phenotypic assessment of galanin overexpressing and galanin receptor R1 knockout mice in the tail suspension test for depression-related behavior

A Holmes, Q Li, EA Koenig, E Gold, D Stephenson… - …, 2005 - Springer
… GAL-tg and GAL-R1 KO mice show evidence of altered … KO mouse models, in combination
with pharmacological approaches, to assess the role of endogenous and exogenous galanin

Mice deficient for galanin receptor 2 have decreased neurite outgrowth from adult sensory neurons and impaired pain‐like behaviour

SA Hobson, FE Holmes, NCH Kerr… - Journal of …, 2006 - Wiley Online Library
… organotypic cultures from Gal-KO mice and mice with an absence of … mice deficient for
GalR2, and demonstrate that the receptor appears to transduce the neuritogenic effects of galanin

Analyzing the validity of GalR1 and GalR2 antibodies using knockout mice

X Lu, T Bartfai - Naunyn-Schmiedeberg's archives of pharmacology, 2009 - Springer
… All antibodies used in these studies were polyclonal antibodies raised against immunogens
10 to 22 amino acids in length corresponding to mouse galanin receptor sequences. …

Phenotypic analysis of mice deficient in the type 2 galanin receptor (GALR2)

ML Gottsch, H Zeng, JG Hohmann… - … and Cellular Biology, 2005 - Taylor & Francis
… observations in GALR2 KO mice (Citation30). Our results show that GALR2 KO mice are
not all that different from GALR1 KO mice except that GALR1 mice exhibit anxiety behaviors (…