Effects of galanin receptor 2 and receptor 3 knockout in mouse models of acute seizures
M Drexel, F Sternberg, B Kofler, G Sperk - Epilepsia, 2018 - Wiley Online Library
… Fisher's exact test was used for analysis of the effect of threshold dose PTZ in galanin
receptor KO mice and WT littermates. One-way analysis of variance (ANOVA) with Bonferroni's …
receptor KO mice and WT littermates. One-way analysis of variance (ANOVA) with Bonferroni's …
Feeding behaviour in galanin knockout mice supports a role of galanin in fat intake and preference
… saline-treated GKO group compared to galanin-treated GKO animals (0.32 … galanin specifically
regulates fat intake, and implies that an antagonist to one or more of the galanin receptor …
regulates fat intake, and implies that an antagonist to one or more of the galanin receptor …
Galanin and galanin receptors in epilepsy
AM Mazarati - Neuropeptides, 2004 - Elsevier
… galanin receptor agonists with anticonvulsant properties. We also address recently established
functions of galanin … more severe seizures in galanin peptide knockout mice, compared to …
functions of galanin … more severe seizures in galanin peptide knockout mice, compared to …
[125I]-Galanin binding in brain of wildtype, and galanin-and GalR1-knockout mice: strain and species differences in GalR1 density and distribution
SRF Jungnickel, AL Gundlach - Neuroscience, 2005 - Elsevier
… [ 125 I]-galanin (GAL) binding sites in brain of the common C57BL/6J and 129OlaHsd mouse
strains, as well as in GAL and galanin receptor-1 (GalR1) knockout (KO) mice. In C57BL/6J …
strains, as well as in GAL and galanin receptor-1 (GalR1) knockout (KO) mice. In C57BL/6J …
Galanin and spinal nociceptive mechanisms: recent results from transgenic and knock-out models
Z Wiesenfeld-Hallin, XJ Xu, JN Crawley, T Hökfelt - Neuropeptides, 2005 - Elsevier
… Genetically modified mice with transgenic overexpression of galanin or depletion of genes
for galanin or galanin receptors have become available, providing a new approach for …
for galanin or galanin receptors have become available, providing a new approach for …
Sensory neuronal phenotype in galanin receptor 2 knockout mice: focus on dorsal root ganglion neurone development and pain behaviour
TJS Shi, X Hua, X Lu, S Malkmus… - European Journal of …, 2006 - Wiley Online Library
… Galanin receptor 2 null mutation-carrying mice have been difficult to generate using …
receptors. The insertion of the neo-cassette into the GalR2 intron has, however, produced a mouse …
receptors. The insertion of the neo-cassette into the GalR2 intron has, however, produced a mouse …
Phenotypic assessment of galanin overexpressing and galanin receptor R1 knockout mice in the tail suspension test for depression-related behavior
… GAL-tg and GAL-R1 KO mice show evidence of altered … KO mouse models, in combination
with pharmacological approaches, to assess the role of endogenous and exogenous galanin …
with pharmacological approaches, to assess the role of endogenous and exogenous galanin …
Mice deficient for galanin receptor 2 have decreased neurite outgrowth from adult sensory neurons and impaired pain‐like behaviour
SA Hobson, FE Holmes, NCH Kerr… - Journal of …, 2006 - Wiley Online Library
… organotypic cultures from Gal-KO mice and mice with an absence of … mice deficient for
GalR2, and demonstrate that the receptor appears to transduce the neuritogenic effects of galanin …
GalR2, and demonstrate that the receptor appears to transduce the neuritogenic effects of galanin …
Analyzing the validity of GalR1 and GalR2 antibodies using knockout mice
X Lu, T Bartfai - Naunyn-Schmiedeberg's archives of pharmacology, 2009 - Springer
… All antibodies used in these studies were polyclonal antibodies raised against immunogens
10 to 22 amino acids in length corresponding to mouse galanin receptor sequences. …
10 to 22 amino acids in length corresponding to mouse galanin receptor sequences. …
Phenotypic analysis of mice deficient in the type 2 galanin receptor (GALR2)
ML Gottsch, H Zeng, JG Hohmann… - … and Cellular Biology, 2005 - Taylor & Francis
… observations in GALR2 KO mice (Citation30). Our results show that GALR2 KO mice are
not all that different from GALR1 KO mice except that GALR1 mice exhibit anxiety behaviors (…
not all that different from GALR1 KO mice except that GALR1 mice exhibit anxiety behaviors (…
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