… with stage IV lung adenocarcinomas, EGFR and KRAS mutations would identify patients
with … with advanced lung adenocarcinomas and known EGFR and KRAS mutation status. We …

… investigated EGFR and KRAS mutational status in metastatic lung adenocarcinomas using
… Taken together, our data demonstrated that 1 tumor lost the EGFR mutation in its metastatic …

… in lung adenocarcinoma—EGFR and KRAS mutations—that already have known biologic
and therapeutic relevance. Both mutations are oncogenic and importantly, EGFR mutations …

… , our data suggested that the lung adenocarcinomas with the EGFR mutations might comprise
an adenocarcinoma group that is distinct from those with K-RAS mutations. Therefore, the …

… mutations. The overall frequency of EGFR mutations in lung adenocarcinomas in this West
… , whereas KRAS mutation frequency is higher than in any population described to date. …

… of lung adenocarcinomas [10,14]. The high incidence of EGFR mutations in East Asians with
lung adenocarcinomas may explain the lower frequency of KRAS mutations in East Asians …

… KRAS mutations and EGFR mutations are mutually exclusive, and the presence … EGFR and
KRAS mutations in the largest cohort of African American patients with lung adenocarcinoma …

… EGFR and KRAS mutations, and EGFR gene copy number in a clinically selected population
of patients with advanced stage lung adenocarcinoma … , both EGFR mutations and gain of …

… We showed that none of the mixed type adenocarcinomas with EGFR mutations showed
a dominant solid growth pattern. In addition, logistic regression analysis for the first time …

… In 6 of 7 cases with an EGFR mutation and in 25 of 36 cases with a KRAS mutation, we
found a discordant mutational status in the primary tumor and the corresponding lymph node …