Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression
X Zhang, S Zhang, X Yang, J Yang, Q Zhou, L Yin… - Molecular cancer, 2010 - Springer
… % (10/62) in patients with adenocarcinomas, 19.23% (10/52) … with adenocarcinomas lacking
EGFR and KRAS mutations. … ), and adenocarcinomas without EGFR/KRAS mutations (P = …
EGFR and KRAS mutations. … ), and adenocarcinomas without EGFR/KRAS mutations (P = …
Activation status of receptor tyrosine kinase downstream pathways in primary lung adenocarcinoma with reference of KRAS and EGFR mutations
M Hiramatsu, H Ninomiya, K Inamura, K Nomura… - Lung Cancer, 2010 - Elsevier
… lung adenocarcinoma, one is the vestige of normal intracellular signal and the other is the
impact of KRAS mutation. … significantly expressed in cases with the EGFR mutation (p = 0.008) …
impact of KRAS mutation. … significantly expressed in cases with the EGFR mutation (p = 0.008) …
[HTML][HTML] Ethnicity affects EGFR and KRAS gene alterations of lung adenocarcinoma
… (EGFR CNG independent of EGFR mutation), mKRAS and g… , the EGFR and KRAS profiles
in lung adenocarcinoma differ … affects the molecular characteristics of lung adenocarcinoma. …
in lung adenocarcinoma differ … affects the molecular characteristics of lung adenocarcinoma. …
[HTML][HTML] Differences in EGFR and KRAS mutation spectra in lung adenocarcinoma of never and heavy smokers
K Takamochi, S Oh, K Suzuki - Oncology Letters, 2013 - spandidos-publications.com
… EGFR mutations are … the EGFR- or KRAS-mutated lung adenocarcinomas other than tumor
size, indicating that smoking status has a greater effect on the cause of lung adenocarcinoma …
size, indicating that smoking status has a greater effect on the cause of lung adenocarcinoma …
Micropapillary Lung Adenocarcinoma: EGFR, K-ras, and BRAF Mutational Profile
R De Oliveira Duarte Achcar… - American journal of …, 2009 - academic.oup.com
… , our micropapillary adenocarcinomas produced mucin and had EGFR mutations, as well …
K-ras, EGFR, and BRAF mutations occur at an increased frequency in lung adenocarcinomas …
K-ras, EGFR, and BRAF mutations occur at an increased frequency in lung adenocarcinomas …
… Mutations and Histologic Patterns of Mucin in Lung Adenocarcinoma: Invasive Mucinous Pattern and Extracellular Mucin Are Associated With: KRAS: Mutation
K Kadota, YC Yeh, SP D'Angelo… - The American journal …, 2014 - journals.lww.com
… Further, in the current study, solid-predominant tumors were associated with KRAS mutations
compared with EGFR mutations; however, acinar-predominant, papillary-predominant, and …
compared with EGFR mutations; however, acinar-predominant, papillary-predominant, and …
Simplified molecular classification of lung adenocarcinomas based on EGFR, KRAS, and TP53 mutations
… and had tumors enriched for EGFR mutations. Worse overall survival was associated with
older age, stage IV disease, and tumors with co-mutations in KRAS and TP53. Interestingly, …
older age, stage IV disease, and tumors with co-mutations in KRAS and TP53. Interestingly, …
Analysis of EGFR, EML4-ALK, KRAS, and c-MET mutations in Chinese lung adenocarcinoma patients
N Xia, J An, Q Jiang, M Li, J Tan… - Experimental lung research, 2013 - Taylor & Francis
… the KRAS mutation, which is consistent with the report stating that this mutation is rare in Asian
lung adenocarcinoma … Our data also demonstrated that KRAS and EGFR mutations were …
lung adenocarcinoma … Our data also demonstrated that KRAS and EGFR mutations were …
Unique microRNA‐profiles in EGFR‐mutated lung adenocarcinomas
MM Bjaanæs, AR Halvorsen, S Solberg… - … journal of cancer, 2014 - Wiley Online Library
… of lung adenocarcinomas and corresponding normal lung tissue and correlated the expression
with clinical data and EGFR- and KRAS-… KRAS mutations in 148 lung adenocarcinoma …
with clinical data and EGFR- and KRAS-… KRAS mutations in 148 lung adenocarcinoma …
Identification of EGFR mutation, KRAS mutation, and ALK gene rearrangement in cytological specimens of primary and metastatic lung adenocarcinoma
G Cai, R Wong, D Chhieng, GH Levy… - Cancer …, 2013 - Wiley Online Library
… The molecular alterations identified in the current study (EGFR mutation, KRAS mutation,
or ALK gene rearrangement) appeared to be mutually exclusive in all lung adenocarcinomas. …
or ALK gene rearrangement) appeared to be mutually exclusive in all lung adenocarcinomas. …