… By contrast, even though KRAS mutations were identified in NSCLC tumors more … KRAS
mutant NSCLC. In this review, we summarize the initial discovery of RAS mutations in NSCLC, …

… (KRAS), and KRAS-mutant NSCLC is associated with smoking. There are various sources of
biological heterogeneity of KRAS-mutant NSCLC, … of other co-mutations that exhibit different …

… developed for patients with KRAS-mutant NSCLC. In this … with NSCLC and with KRAS
mutations, describe work that explores the predictive and prognostic influence of KRAS mutations, …

… KRAS-mutant NSCLC are discordant. This study assessed the routine efficacy of ICIs in
advanced KRAS-mutant NSCLC. … of ICIs is similar in NSCLC with and without KRAS mutation. An …

… In this review, we systematically analyze the clinically relevant aspects of KRAS-mutant
NSCLC, mainly focusing on the clinicopathological relevance, therapeutic implications, and new …

… KRAS mutations represent one of the most prevalent oncogenic driver mutations in non-small
cell lung cancer (NSCLC… we have unsuccessfully addressed KRAS mutation as a unique …

… KRAS neoantigens have sparked a race for approved therapies. Few treatments are available
for KRAS mutant NSCLC … review promising therapeutics tested for KRAS mutant NSCLC. …

… -mutations and their correlation with different KRAS mutation … 1078 patients with NSCLC
harboring KRAS mutations. Using … mutations and their association with KRAS mutation subtypes…

… Here we review, in the context of NSCLC, the underlying biology of KRAS mutations, the
predictive value of KRAS mutations for therapeutic intervention, and the integration of KRAS …

… KRAS mutations are found in 20–25% of NSCLC and are the … of KRAS-mutant NSCLC
have been identified according to their need for mutant KRAS to maintain tumour viability: KRAS-…