… We report the crystal structure at 3.5 angstroms of the Escherichia coli lactose permease,
an … helices, symmetrically positioned within the permease. A large internal hydrophilic cavity …

… Recently, the X-ray structure of the Escherichia coli lactose permease (LacY), an intensively
studied member of a large group of related membrane transport proteins, was solved at 3.5 Å…

We studied the effect of pH on ligand binding in wild-type lactose permease or mutants in the
four residues—Glu-269, Arg-302, His-322, and Glu-325—that are the key participants in H …

… in the cytoplasmic membrane required for lactose/H + symport. 11,12 … lac permease from
membrane to molecule in a fully functional state. As an overview, membranes from a strain of E…

… needed in unfused lac permease after insertion for stable association with the membrane. …
of the biogenesis of Escherichia coli lac permease. lac permease has been the subject of …

… The lactose permease (lac permease) of Escherichia coli is … The lacY gene that encodes
the permease has been cloned … All available evidence indicates that the permease consists of …

Lactose/H + symport in Escherichia coli is catalysed by a … -acid sequence of this ‘ lac ’
permease suggest a secondary … the structure and function of the permease. Application of the …

… Both biotinylated permeases bind selectively to immobilized … The lactose permease of
Escherichia coli is a polytopic … of the approach to lactose permease. Preliminary reports on …

… The lac permease of Escherichia coli is providing a … The lacY gene that encodes the permease
is cloned and … by analyzing a large number of lac permease-alkaline phosphatase (lacY-…

… a concentration gradient in Escherichia coli is dependent on the lactose (lac) permease, a …
H+) is interior-negative and alkaline, lac permease utilizes free energy released from downhill …