In utero and lactational exposure to di (2-ethylhexyl) phthalate increased the susceptibility of prostate carcinogenesis in male offspring

X Wang, Y Wang, Q Song, J Wu, Y Zhao, S Yao… - Reproductive …, 2017 - Elsevier
… and its sensitive exposure window, we hypothesize whether in utero and lactational exposure
of DEHP has any effects on the susceptibility to prostate carcinogenesis in male offspring. …

Lack of carcinogenic risk in the prostate with transplacental and lactational exposure to bisphenol A in rats

T Ichihara, H Yoshino, N Imai, T Tsutsumi… - The Journal of …, 2003 - jstage.jst.go.jp
… ) on prostate cancer risk in male offspring exposed transplacentally and lactationally. BPA
… , 120 mg/kg/day during pregnancy and lactation periods. When F1 males reached 5 weeks …

The initiation of breast and prostate cancer

PL Grover, FL Martin - Carcinogenesis, 2002 - academic.oup.com
lactation both reduce breast cancer risk and the reduction is proportional either to the amount
of tissue removed or to the total duration of lactation… mammoplasty and lactation reduce risk …

… and lactational exposition to Di‐N‐butyl‐phthalate (DBP) increases inflammation and preneoplastic lesions in prostate of wistar rats after carcinogenic N‐methyl‐N …

AR Peixoto, TM Santos, JZ Brandt… - Environmental …, 2016 - Wiley Online Library
… susceptibility of prostatic lesions in male adult rats exposed to Di-N-butyl-phthalate during
fetal and lactational periods and submitted to MNU plus testosterone carcinogenesis protocol. …

In utero and lactational exposure of DEHP increases the susceptibility of prostate carcinogenesis in male offspring through PSCA hypomethylation

B Xia, Y Wang, X Wang, J Wu, Q Song, Z Sun, Y Zhang - Toxicology Letters, 2018 - Elsevier
exposure on prostate carcinogenesis in rodents, we assessed the effect of DEHP exposure
… rats, and evaluated their relationship with prostate carcinogenesis parameters on PND 196. …

… and proteome analysis indicates potential biomarkers of prostate cancer in offspring of pregnant rats exposed to a phthalate mixture during gestation and lactation

AM Aquino, LG Alonso-Costa, SAA Santos, VA Rocha… - Chemosphere, 2023 - Elsevier
… death for cancer among men worldwide, prostate cancer (PCa… alter essential pathways for
prostate gland development and … are exposed to ubiquitously. Here, we show that maternal …

In Uteroand Lactational Exposure of the Male Rat to 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin Impairs Prostate Development

BL Roman, RE Peterson - Toxicology and applied pharmacology, 1998 - Elsevier
… of TCDD in the rat prostate in response to in utero and lactational exposure has not been …
induction in the ventral prostate by PND 21 and in the dorsolateral prostate by PND 32 suggest …

Perinatal exposure to oestradiol and bisphenol A alters the prostate epigenome and increases susceptibility to carcinogenesis

GS Prins, WY Tang, J Belmonte… - Basic & clinical …, 2008 - Wiley Online Library
exposures to hormonally active environmental oestrogens such as bisphenol A can promote
human diseases including prostate cancer. … prostate development result in marked prostate

Maternal low-protein diet impairs prostate growth in young rat offspring and induces prostate carcinogenesis with aging

SAA Santos, AC Camargo… - The Journals of …, 2019 - academic.oup.com
… in offspring rats born to dams fed an LPD during lactation. … impairment of prostate growth
induced by maternal exposure to … prostate of offspring young rats to carcinogenesis with aging. …

Hormonal carcinogenesis

BE Henderson, HS Feigelson - Carcinogenesis, 2000 - academic.oup.com
… We developed polygenic models for breast and prostate cancer after hypothesizing that
functionally relevant sequence variants in genes involved in steroid hormone metabolism and …