Expression of human lactoferrin in milk of transgenic mice

GJ Platenburg, EPA Kootwijk, PM Kooiman… - Transgenic …, 1994 - Springer
gene in the bovine mammary gland. The temporal expression of the transgene in … mouse
is slightly different from endogenous milk protein genes: whereas all murine milk protein genes

High-level expression of human lactoferrin in milk of transgenic mice using genomic lactoferrin sequence

SJ Kim, BH Sohn, S Jeone, KW Pak, JS Park… - The journal of …, 1999 - jstage.jst.go.jp
… (hLF) in milk using cDNA under control of the 2kb bovine ƒÀ-casein promoter. The … in milk
of 7 mice ranged from 1 to 200ƒÊg/ml; 1 to 34ƒÊg/ml in 6 mice and 200 beg/ml in 1 mouse. …

[HTML][HTML] Expression of human lactoferrin in milk of transgenic mice using bovine β-casein/human lactoferrin cDNA fusion gene

SJ Kim, YY Cho, KW Lee, DY Yu, CS Lee, YM Han… - Molecules and …, 1994 - Elsevier
gene, we generated transgenic mouse lines as a model system not only for the mass production
of hLF in the milk of … study reached up to 150∼200 μg/ml in the milk of transgenic mice. …

Expression analysis of a bovine β-casein/human lactoferrin hybrid gene in transgenic mice

SJ Kim, KW Lee, DY Yu, YM HAN, CS LEE… - … of Reproduction and …, 1997 - jstage.jst.go.jp
Lactoferrin (LF) is an iron binding protein in milk and a member of transferrin family [13]. …
mice carrying human lactoferrin cDNA [7]. Regulatory elements of the bovine β-casein gene

Evaluation of behavioral profiles in mice fed with milk supplemented diets derived from human lactoferrin gene-modified cows

S Liu, HB Liu, HL Wang, Y Zhi, XL Feng… - Regulatory Toxicology and …, 2019 - Elsevier
… , behavioral profiles in mice fed with milk derived from human lactoferrin gene-modified …
milk and GM milk were added to diets at a proportion of 7.5%, 15% and 30%(w/w). After the mice

[HTML][HTML] Developmental gene expression of lactoferrin and effect of dietary iron on gene regulation of lactoferrin in mouse mammary gland

Y Wang, Y Tu, F Han, Z Xu, J Wang - Journal of dairy science, 2005 - Elsevier
… the developmental gene expression of lactoferrin (LF) and the effect of supplementary iron on
gene expression of LF in the mammary gland of miceLactoferrin secretion into mouse milk

Lactoferrin secretion into mouse milk: development of secretory activity, the localization of lactoferrin in the secretory pathway, and interactions of lactoferrin with milk …

MC Neville, K Chatfield, L Hansen, A Lewis… - Advances in Lactoferrin …, 1998 - Springer
lactoferrin but not transferrin in the medium after … lactoferrin to quantitate the protein in
mouse milk throughout lactation (Figure 3). Levels varied widely from 0.05 to 0.8 mg/ml in the milk

Production of human lactoferrin in animal milk

IL Goldman, SG Georgieva, YG Gurskiy… - … and Cell Biology, 2012 - cdnsciencepub.com
… (hLf) gene were created within a joint program of Russian … mice were bred (the maximum hLf
concentration in their milk was … human lactoferrin secreted in milk of transgenic mice. J. Biol. …

Recombinant porcine lactoferrin expressed in the milk of transgenic mice enhances offspring growth performance

SC Wu, HL Chen, CC Yen, MF Kuo… - Journal of Agricultural …, 2007 - ACS Publications
mice harboring the pLF gene driven by the mammary gland-specific promoter of the bovine
α-lactalbumin gene… of pLF secreted in milk of transgenic mice and the growth performance in …

Variable expression of human lactoferrin gene in mice milk driven by its 90 KB upstream flanking sequences

Z Liu, C Zhao, B Fan, Y Dai, Z Zhao, L Wang… - Animal …, 2004 - Taylor & Francis
… sequences of the gene. Milk of eight transgenic mice line was detected by Western blot
and radioimmunoassay and seven lines expressed recombinant human lactoferrin at high but …