The role of acetaldehyde outside ethanol metabolism in the carcinogenicity of alcoholic beverages: evidence from a large chemical survey
DW Lachenmeier, EM Sohnius - Food and Chemical Toxicology, 2008 - Elsevier
… Acetaldehyde formed during ethanol metabolism is generally considered as a source of …
outside ethanol metabolism. In this study, we have analysed and evaluated a large sample …
outside ethanol metabolism. In this study, we have analysed and evaluated a large sample …
Chronic ethanol consumption alters mammalian gastrointestinal content metabolites
… as a product of ethanol metabolism. … study, we examined the metabolic profiles of the GI
contents in normal rats and determined how those metabolic profiles were impacted by ethanol …
contents in normal rats and determined how those metabolic profiles were impacted by ethanol …
Ethanol metabolism, toxicity and genetic polymorphism
K IWAHASHI, H SUWAKI - Addiction biology, 1998 - Wiley Online Library
… In the major pathway for alcohol metabolism, ethanol is … ALDH isozymes metabolized to
acetaldehyde mainly by alcohol … A pharmacokinetic study of ethanol elimina93. Whit®eld JB. …
acetaldehyde mainly by alcohol … A pharmacokinetic study of ethanol elimina93. Whit®eld JB. …
Ethanol metabolism in the liver, the induction of oxidant stress, and the antioxidant defense system
ML Contreras-Zentella, D Villalobos-García… - Antioxidants, 2022 - mdpi.com
… Inhibitors have been widely used to study the contribution of each metabolic pathway to
ethanol oxidation; however, the lack of specific selectivity is a serious drawback. Fomepizole is a …
ethanol oxidation; however, the lack of specific selectivity is a serious drawback. Fomepizole is a …
Carcinogenicity of acetaldehyde in alcoholic beverages: risk assessment outside ethanol metabolism
DW Lachenmeier, F Kanteres, J Rehm - Addiction, 2009 - Wiley Online Library
… For our evaluation of acetaldehyde outside ethanol metabolism it is interesting to note that
… The major result from this study is the fact that acetaldehyde outside ethanol metabolism …
… The major result from this study is the fact that acetaldehyde outside ethanol metabolism …
The role of alcohol dehydrogenase in drug metabolism: beyond ethanol oxidation
L Di, A Balesano, S Jordan, SM Shi - The aaps journal, 2021 - Springer
… to ethanol metabolism when the concentration is high. ADH5 has very low affinity for ethanol
and contributes minimally to ethanol metabolism … However, ADH5 can metabolize ethanol in …
and contributes minimally to ethanol metabolism … However, ADH5 can metabolize ethanol in …
… a physiologically-based pharmacokinetic model with a whole-body, organ-resolved genome-scale model for characterization of ethanol and acetaldehyde metabolism
… of ethanol metabolism through alcohol dehydrogenase have … and genetic variations on
ethanol metabolism. This combined … In this study, we combined a PBPK model with a GEM to …
ethanol metabolism. This combined … In this study, we combined a PBPK model with a GEM to …
In vivo metabolic tracing demonstrates the site‐specific contribution of hepatic ethanol metabolism to histone acetylation
CL Kriss, E Gregory‐Lott, AJ Storey… - Alcoholism: Clinical …, 2018 - Wiley Online Library
… This study describes a novel in vivo metabolic tracing approach using high-resolution
mass … histone acetylation influenced directly by ethanol metabolism. Using stable isotope-labeled …
mass … histone acetylation influenced directly by ethanol metabolism. Using stable isotope-labeled …
… methodology to build a multifactorial statistical model describing the metabolic interactions of alcohol dehydrogenase isozymes in the ethanol biosynthetic pathway of …
… a positive impact on ethanol production only under anaerobic … model of ethanol production
under anaerobic aeration and in high … experimental data sets as exemplified within this study. …
under anaerobic aeration and in high … experimental data sets as exemplified within this study. …
Microbial physiology-based model of ethanol metabolism in subsurface sediments
… ethanol amendment impacts subsurface environments, we describe here a biogeochemical
reaction model of ethanol metabolism. … This study estimates the m ATP values based on the …
reaction model of ethanol metabolism. … This study estimates the m ATP values based on the …
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