… In conclusion, through a genetic association study on in and around the APOE, we found
that three additional genes, PVRL2, TOMM40 and APOC1, exhibited significant association …

… APOE2/3 individuals had very late age-of-onset perhaps indicating that APOE2 was a …
initial genetic association with sporadic AD and continued the subsequent experiments and later …

… The results of this study establish a genetic association between CST3 B/B and AD. There …
a risk factor for late-onset AD. Although statistically significant in this association study, it may …

… for late-onset disease has been attributed to alleles at the apolipoprotein E (ApoE) locus.
We have looked for an association between PS-1 and late-onset … for association with lateonset …

… genetic risks could exist. To reveal the ones for late-onset AD (LOAD), we extended our
previous genetic work … (SNP)-based genetic association analyses were performed on the same …

… with younger age of disease onset. In our genetic association study, although the subjects
… Thus, we used an additional experimental approach to assess the potential association of …

… Conceivably, mutations in these genes may play a role in affecting AD susceptibility, which
… by some genetic studies. Here we report results of the first genetic association study with …

Since a deletion/insertion polymorphism in the promoter region of the apolipoprotein CI (APOC1)
gene has been reported to be associated with late-onset Alzheimer's disease (LOAD), …

A variable-length poly-T variant in intron 6 of the TOMM40 gene, rs10524523, is associated
with risk and age-of-onset of sporadic (late-onset) Alzheimer's disease. In Caucasians, the …

Rare non-synonymous variants of TREM2 have recently been shown to be associated with
Alzheimer’s disease (AD) in Caucasians. We here conducted a replication study using a well-…