… first realistic experimental strategy for validation of drug targets for the treatment of latent TB.
… model for testing the ability of candidate drugs to eradicate latent TB. But given the time, cost …

… Treatment of latent tuberculosis (LTBI) is a vital component of tuberculosis (TB) elimination
but … Treatment of LTBI with isoniazid targets actively replicating bacilli but not non-replicating …

… strategies for targeting latent tuberculosis, new candidate drug targets as well as important
lead clues for drug … was to identify potential drug targets for latent TB. Transcriptome data was …

… Since currently used antibiotics target DNA replication, transcription, translation, or aspects
… a dormant or non-replicative state and successfully evade any immune response. Latent TB …

… and treating latent tuberculosis (TB) infection (LTBI) is … strategy to accelerate the decline in
global TB and achieve … Whether a single drug, or a combination of drugs targeting growing …

… by 2050 is a bold one and the development of the post-2015 TB strategy and targets
provides an opportunity to identify the critical gaps in our knowledge and to focus the scientific …

… Policies for the programmatic management of latent TB should consider the risk of
progression of latent TB infection into active TB disease and those factors that determine it. For …

… , tuberculosis (TB) is still the leading cause of death from a single infectious agent worldwide.
Latent TB infection (LTBI) has been recognized as the largest source of new TB cases and …

… strategies for the development and application of drugs to … of several anti-tubercular drug
targets including isoniazid (and … been used to study potential drug targets in subsystems of the …

… dormant TB bacteria is thought to be the cause for the lengthy TB chemotherapy, since the
current TB drugs … therapeutic strategies targeting the persistent or dormant organisms. Natural …