[HTML][HTML] Updated frequency of EGFR and KRAS mutations in nonsmall-cell lung cancer in Latin America: the Latin-American Consortium for the Investigation of Lung …

O Arrieta, AF Cardona, C Martín, L Más-López… - Journal of Thoracic …, 2015 - Elsevier
… of NSCLC in Latin America, confirming that the frequency of EGFR mutations is intermediate
… In this report, we update the frequency of EGFR and KRAS mutations in Latin America, …

Uptake of KRAS mutation testing in patients with metastatic colorectal cancer in Europe, Latin America and Asia

F Ciardiello, S Tejpar, N Normanno, D Mercadante… - Targeted …, 2011 - Springer
… (28 of 139) of participating physicians in Europe, Latin America and Asia, respectively,
reported that they would routinely request a tumor KRAS mutation test at the time of diagnosis of …

KRAS Exon 2 Mutations in Patients with Sporadic Colorectal Cancer: Prevalence Variations in Mexican and Latin American Populations

JL Venegas-Rodríguez, JA Hernández-Sandoval… - Cancers, 2024 - mdpi.com
… from Latin America focusing on determining the KRAS mutation … low-income countries in
Latin America, where economic fac… prevalence of KRAS exon 2 mutations in Latin America may …

[HTML][HTML] Genotyping non-small cell lung cancer (NSCLC) in Latin America

O Arrieta, AF Cardona, GF Bramuglia, A Gallo… - Journal of Thoracic …, 2011 - Elsevier
… that EGFR and KRAS mutations are mutually … KRAS mutation may coexist with EGFR
mutation (4.6%), similar to a previous report. We also found a higher frequency of KRAS mutations

Frequency of KRAS p.Gly12Cys Mutation in Brazilian Patients With Lung Cancer

R Cavagna, F Escremim de Paula, D Sant'Anna… - JCO Global …, 2021 - ascopubs.org
… A study involving 5,738 NSCLC cases reported 14% of KRAS-mutated cases in Latin
American except for Brazil (Argentina, Mexico, Colombia, Peru, Costa Rica, and Panama). …

[HTML][HTML] p. G12C KRAS mutation prevalence in non-small cell lung cancer: Contribution from interregional variability and population substructures among Hispanics

A Ruiz-Patino, J Rodríguez, AF Cardona, J Ávila… - Translational …, 2022 - Elsevier
… The genomic landscape of LUADs is strikingly varied in Latin American patients with mixed
ancestries. Previous studies demonstrated that native ancestry was correlated with somatic …

Prevalence of oncogenic driver mutations in Hispanics/Latin patients with lung cancer. A systematic review and meta-analysis

R Parra-Medina, JP Castañeda-González, L Montoya… - Lung Cancer, 2023 - Elsevier
… The prevalence of driver mutations in Latin American patients eg, EGFR and KRAS, differs
from what has been reported in Asians and Europeans. Countries with a high proportion of …

Molecular characterization of non-small cell lung cancer tumors in Latin American patients from Brazil, Chile and Peru uncovers novel potentially driver mutations

G Sepúlveda-Hermosilla, A Blanco, M Freire, R Lizana… - medRxiv, 2020 - medrxiv.org
… On the other hand, Kras mutations prevalence is statistically similar between Brazil (23%)
and MSKCC (27%), while significantly lower in Chile (16%) and Peru (9%); while prevalence …

[HTML][HTML] Mutational landscape of gastric adenocarcinoma in Latin America: A genetic approach for precision medicine

D Cerrato-Izaguirre, YI Chirino, CM García-Cuellar… - Genes & …, 2022 - Elsevier
… novel drugs with targeted activity to KRAS p.G12D variant in non… Another Colombian study
identified that some KRAS somatic … relevant mutations and the non-actionable mutation are re-…

Genetic ancestry contributes to somatic mutations in lung cancers from admixed Latin American populations

J Carrot-Zhang, G Soca-Chafre, N Patterson… - Cancer discovery, 2021 - AACR
… of somatic EGFR and KRAS mutations in lung cancer varies by ethnicity, but we do not
understand why. Our study suggests that the variation in EGFR and KRAS mutation frequency is …