LCMS/MS analysis of permethylated free oligosaccharides and N‐glycans derived from human, bovine, and goat milk samples

X Dong, S Zhou, Y Mechref - Electrophoresis, 2016 - Wiley Online Library
LC coupled with MS would provide most comprehensive qualitative and quantitative analyses
of milk oligosaccharides. However, the quantitation of acidic milk oligosaccharides may be …

Comparative analysis of oligosaccharides in Guanzhong and Saanen goat milk by using LCMS/MS

J Lu, Y Zhang, B Song, S Zhang, X Pang, RN Sari… - Carbohydrate …, 2020 - Elsevier
… but also the diversity of goat milk OS are higher than that of bovine milk. Therefore, goat
milk oligosaccharides could be a better potential substitute for human milk oligosaccharide. …

Simple liquid chromatography–mass spectrometry method for quantification of major free oligosaccharides in bovine milk

Z Liu, P Moate, B Cocks, S Rochfort - Journal of agricultural and …, 2014 - ACS Publications
LCMS systems have been reported thus far for milk OS analysis. For example, Fong et al.
developed a LC–triple quadruple/MS … and validation of a LCMS method for the quantitative …

[HTML][HTML] Comparison of different labeling techniques for the LC-MS profiling of human milk oligosaccharides

Y Lang, Y Zhang, C Wang, L Huang, X Liu… - Frontiers in …, 2021 - frontiersin.org
… Putative structures can be assigned based on known human milk oligosaccharide patterns:
glycan … more tools and methods to bring the science of human milk oligosaccharides forward. …

Comparative analysis of native and permethylated human milk oligosaccharides by liquid chromatography coupled to high resolution mass spectrometry

S Oursel, S Cholet, C Junot, F Fenaille - Journal of Chromatography B, 2017 - Elsevier
… (LCMS) for analyzing HMOs. We have implemented and thoroughly compared the LCMS
of … to resolve the natural heterogeneity of milk oligosaccharides at the highest sensitivity. Our …

Combining HPAEC-PAD, PGC-LCMS, and 1D 1H NMR to Investigate Metabolic Fates of Human Milk Oligosaccharides in 1-Month-Old Infants: a Pilot Study

F Gu, GA Kate, ICW Arts, J Penders… - Journal of Agricultural …, 2021 - ACS Publications
… of age, making human milk the preferred sole source of nutrition in the first months of life. (1)
As the third most abundant component in human milk, human milk oligosaccharides (HMOs) …

Characterization and quantification of oligosaccharides in human milk and infant formula

RM Nijman, Y Liu, A Bunyatratchata… - Journal of agricultural …, 2018 - ACS Publications
Oligosaccharide Analysis by Nano-LC-Chip/Q-TOF Purified reduced milk oligosaccharides
were analyzed by nano-LC-chip/Q-TOF mass spectrometry. Samples were rehydrated in 50 …

[HTML][HTML] Simultaneous determination of neutral and acidic human milk oligosaccharides (HMOs) by liquid chromatography with tandem mass spectrometry (LC-MS/MS …

J Tan, HH Lee, L Wong, C Fong, A Ong, Q Lin… - Applied Food …, 2022 - Elsevier
… Human milk oligosaccharides (HMOs) are a complex category of glycans present in high
abundance in human milk, with its concentration and composition closely associated with infant …

[HTML][HTML] Advances in analysis of human milk oligosaccharides

LR Ruhaak, CB Lebrilla - Advances in Nutrition, 2012 - Elsevier
… Our laboratory recently introduced nano-LC PGC chip time-of-flight (TOF) MS in the positive
mode for the analysis of HMO (7, 8, 46). In this method, good isomer separation is combined …

Label-free targeted LC-ESI-MS2 analysis of human milk oligosaccharides (HMOS) and related human milk groups with enhanced structural selectivity

M Mank, P Welsch, AJR Heck, B Stahl - Analytical and Bioanalytical …, 2019 - Springer
… Therefore, we developed a negative ion mode LC-ESI-MS 2 … Our MRM-LC-MS setup takes
advantage of highly selective, … Notably, many human milk oligosaccharide isomers could be …