Sensitive assay for determining plasma tenofovir concentrations by LC/MS/MS

T Delahunty, L Bushman, CV Fletcher - Journal of chromatography B, 2006 - Elsevier
… A pharmacokinetic study of TNF in children that used LCMS has recently been reported,
but … This report describes an LC/MS/MS method to determine TNF concentrations in plasma

Evaluation of coagulation assays versus LC-MS/MS for determinations of dabigatran concentrations in plasma

JP Antovic, M Skeppholm, J Eintrei, EE Boija… - European journal of …, 2013 - Springer
plasma concentrations by LC-MS/MS should be considered to be the reference method of
choice. The LC-MS/MS … indirect assessments of dabigatran concentrations in clinical samples …

[HTML][HTML] Reference intervals for plasma concentrations of adrenal steroids measured by LC-MS/MS: impact of gender, age, oral contraceptives, body mass index and …

G Eisenhofer, M Peitzsch, D Kaden, K Langton… - Clinica Chimica …, 2017 - Elsevier
… In summary, this study outlines gender and age-specific reference intervals for LC-MS/MS-derived
measurements of plasma concentrations for 16 steroids in a panel designed primarily …

Determination of plasma concentration of Belimumab by LC-MS/MS: method development, validation, and clinical application

C Marin, G Noé, D Schlemmer, Q Beaulieu… - … of Pharmaceutical and …, 2023 - Elsevier
… a method for LC-MS/MS quantification of belimumab in plasma samples. … of LC-MS/MS.
During phase I/II and III trial, belimumab levels were determined by ELISA, and the concentration

A sensitive assay for simultaneous determination of plasma concentrations of valganciclovir and its active metabolite ganciclovir by LC/MS/MS

HR Xu, XN Li, WL Chen, GY Liu, NN Chu… - Journal of Chromatography …, 2007 - Elsevier
LC/MS/MS and the analytes had almost no retention. The purpose of this study was to improve
the LC/MS/MS … and ganciclovir in human plasma to support a pharmacokinetic study after …

Quantitative determination of clopidogrel active metabolite in human plasma by LCMS/MS

M Takahashi, H Pang, K Kawabata, NA Farid… - … of pharmaceutical and …, 2008 - Elsevier
plasma concentrations of clopidogrel AM determined by the previous method probably do
not accurately represent its concentrations in human plasma… the plasma concentrations of the …

Matrix effect in quantitative LC/MS/MS analyses of biological fluids: a method for determination of finasteride in human plasma at picogram per milliliter concentrations

BK Matuszewski, ML Constanzer… - Analytical …, 1998 - ACS Publications
… linear least-squares regression of the plasma concentrations and the measured peak area
ratios… with concentrations of 0.25, 0.5, 1.0, 5.0, 10.0, 50, 100, 500, and 1000 ng/mL for plasma

… of nine antidepressants and some of their main metabolites in oral fluid and plasma: Study of correlation between venlafaxine concentrations in both matrices

A De Castro, M Concheiro, O Quintela, A Cruz… - … of Pharmaceutical and …, 2008 - Elsevier
In this paper, a fast, sensitive and selective LCMS/MS method is described for the
simultaneous determination of amitriptyline, imipramine, clomipramine, fluoxetine, paroxetine, …

Simultaneous LC-MS/MS analysis of the plasma concentrations of a cocktail of 5 cytochrome P450 substrate drugs and their metabolites

S Tanaka, S Uchida, N Inui, K Takeuchi… - Biological and …, 2014 - jstage.jst.go.jp
… rapid and selective LC-MS/MS method for determining the plasma concentrations of 5 CYP
… ) by single-step extraction, followed by a single LC-MS/MS run. An Ostro™ 96-well plate was …

LCMS/MS for the simultaneous analysis of arachidonic acid and 32 related metabolites in human plasma: basal plasma concentrations and aspirin-induced changes …

DD Shinde, KB Kim, KS Oh, N Abdalla, KH Liu… - … of Chromatography B, 2012 - Elsevier
… The results were expressed as mean ± SD and the concentrations below LLOQ were
considered zero. Plasma concentrations of eicosanoids before and 2 h after aspirin administration …