Pathogenic role of modified LDL antibodies and immune complexes in atherosclerosis

MF Lopes-Virella, G Virella - Journal of Atherosclerosis and …, 2013 - jstage.jst.go.jp
LDL antibodies and antiLDL immune complexes in the general population. Journal of
lipid research, 2005; 46: 452-457 97) Tsimikas S, Bergmark C, Beyer RW, Patel R, Pattison J, …

Anti-modified LDL antibodies, LDL-containing immune complexes, and susceptibility of LDL to in vitro oxidation in patients with type 2 diabetes.

MA Mironova, RL Klein, GT Virella… - Diabetes, 2000 - Am Diabetes Assoc
immune response leading to the production of autoantibodies and subsequently to the formation
of atherogenic immune complexes (… Serum antibodies to oxidized and glycated LDL did …

[HTML][HTML] Influence of age and sex on levels of anti-oxidized LDL antibodies and anti-LDL immune complexes in the general population

FJ Tinahones, JM Gómez-Zumaquero… - Journal of lipid …, 2005 - ASBMB
… levels of anti-oxidized LDL (MDA-LDL) antibodies and anti-LDL immune complexes. … LDL
antibodies (P < 0.0001). No difference was seen in the levels of anti-LDL immune complexes. …

Antibodies to oxidized LDL and LDL-containing immune complexes as risk factors for coronary artery disease in diabetes mellitus

MF Lopes-Virella, G Virella, TJ Orchard, S Koskinen… - Clinical …, 1999 - Elsevier
… of free antibody levels. The present report extends the study of oxLDL-IC (immune
complexes) to an IDDM patient population in which we have shown that decreased antibodies to …

Low Density Lipoprotein‐Containing Circulating Immune Complexes: Role in Atherosclerosis and Diagnostic Value

IA Sobenin, JT Salonen, AV Zhelankin… - BioMed Research …, 2014 - Wiley Online Library
… with autologous LDL-containing immune complexes … -LDL antibodies with modified LDL
increases their atherogenic potential. After forming an immune complex with anti-LDL antibodies

Anti-modified LDL antibodies and LDL-containing immune complexes in IDDM patients and healthy controls

M Mironova, G Virella, I Virella-Lowell… - Clinical Immunology and …, 1997 - Elsevier
Antibodies to oxidized LDL (ox-LDL) and LDL-containing immune complexes (LDL-IC) have
been reported to be associated with the presence or progression of arteriosclerosis. We …

Modified LDL immune complexes and cardiovascular disease

MF Lopes-Virella, G Virella - Current Medicinal Chemistry, 2019 - ingentaconnect.com
… Abstract: Modified forms of LDL, both spontaneously formed … , antigen-antibody complexes
(immune complexes, IC) formed … possible to generate antibodies that recognize different LDL

Soluble LDL-immune complexes in type 2 diabetes and vascular disease

Z Turk, M Šesto, J Skodlar, G Ferenčak… - Hormone and …, 2002 - thieme-connect.com
… In this study, we evaluated antibodies to oxidatively modified LDL and circulating LDL-immune
complexes in diabetic patients with micro- and macrovascular disease. Autoantibodies …

[HTML][HTML] Development of immunoassays for anti-electronegative LDL autoantibodies and immune complexes

TE Santo Faulin, KCM de Sena-Evangelista… - Clinica Chimica …, 2012 - Elsevier
… ► LDL(−) promotes atherosclerosis through inflammatory and immunologic mechanisms.
► We developed ELISAs to anti-LDL(−) autoantibodies and its immune complexes. ► The …

[HTML][HTML] Simvastatin efficiently lowers small LDL-IgG immune complex levels: a therapeutic quality beyond the lipid-lowering effect

G Hörl, H Froehlich, U Ferstl, G Ledinski, J Binder… - PLoS …, 2016 - journals.plos.org
… low-density lipoprotein (LDL) subfraction targeted by IgG and the influence of statin
therapy on plasma levels of these small LDL-IgG-immune complexes (LDL-IgG-IC). LDL-subfractions …