[HTML][HTML] IgA nephropathy: the lectin pathway and implications for targeted therapy
J Barratt, RA Lafayette, H Zhang, V Tesar, BH Rovin… - Kidney International, 2023 - Elsevier
… Emerging research suggests that the lectin pathway may also contribute to tubulointerstitial
… of the lectin pathway in IgAN and examines the possible therapeutic role of lectin pathway …
… of the lectin pathway in IgAN and examines the possible therapeutic role of lectin pathway …
Glomerular activation of the lectin pathway of complement in IgA nephropathy is associated with more severe renal disease
A Roos, MP Rastaldi, N Calvaresi… - Journal of the …, 2006 - journals.lww.com
… The lectin pathway can be activated by binding of mannose-binding lectin (MBL) and ficolins
to … This study examined the potential role of the lectin pathway in IgAN. Renal biopsies of …
to … This study examined the potential role of the lectin pathway in IgAN. Renal biopsies of …
Current understanding of the role of complement in IgA nephropathy
… Of three complement-activation pathways, the alternative and lectin pathways are involved
in IgA nephropathy. IgA1 can activate both pathways in vitro, and pathway components are …
in IgA nephropathy. IgA1 can activate both pathways in vitro, and pathway components are …
Inhibition of the lectin pathway of the complement system as a novel approach in the management of IgA vasculitis-associated nephritis
H Selvaskandan, C Kay Cheung, J Dormer, D Wimbury… - Nephron, 2020 - karger.com
… IgA vasculitis can present as a glomerulonephritis histologically indistinguishable from IgA
nephropathy (IgAN). In IgAN, the alternative and lectin pathways mediate glomerular injury …
nephropathy (IgAN). In IgAN, the alternative and lectin pathways mediate glomerular injury …
Role of complement in IgA nephropathy
MR Daha, C van Kooten - Journal of nephrology, 2016 - Springer
… The activation of C3 can also occur via the lectin pathway. In this pathway, targets of the
lectin pathway can be recognized by the pattern-like recognition molecule mannan-binding …
lectin pathway can be recognized by the pattern-like recognition molecule mannan-binding …
Glomerular deposition of mannose-binding lectin (MBL) indicates a novel mechanism of complement activation in IgA nephropathy.
M Endo, H Ohi, I Ohsawa, T Fujita… - … Official Publication of …, 1998 - academic.oup.com
… lectin pathway was involved in the pathogenic mechanism of … the lectin pathway in IgA-N will
provide insights into Briefly, … /MASP-1 to prove that the lectin pathway immersed in methanol …
provide insights into Briefly, … /MASP-1 to prove that the lectin pathway immersed in methanol …
Activation of the lectin complement pathway in Henoch-Schönlein purpura nephritis
S Hisano, M Matsushita, T Fujita, H Iwasaki - American journal of kidney …, 2005 - Elsevier
… with IgA GN, and in those with mesangial IgA1 and IgA2 deposits, both the alternative and
lectin pathways … the lectin pathway in patients with IgA GN. Complement activation through the …
lectin pathways … the lectin pathway in patients with IgA GN. Complement activation through the …
Mesangial IgA2 deposits and lectin pathway-mediated complement activation in IgA glomerulonephritis
S Hisano, M Matsushita, T Fujita, Y Endo… - American journal of …, 2001 - Elsevier
… lectin pathways are involved in complement activation. We first report that mesangial deposits
of IgA2 may activate the lectin pathway in patients with IgA … in childhood IgA nephropathy …
of IgA2 may activate the lectin pathway in patients with IgA … in childhood IgA nephropathy …
New insights into the pathogenesis of IgA nephropathy
… pathway (properdin and factor H) [121, 122] and lectin pathway (mannan-binding lectin (MBL…
Furthermore, the presence of lectin pathway components C4d [126,127,128] and MBL [129] …
Furthermore, the presence of lectin pathway components C4d [126,127,128] and MBL [129] …
The pathophysiology of IgA nephropathy
H Suzuki, K Kiryluk, J Novak… - Journal of the …, 2011 - journals.lww.com
… The immune complexes with IgA1 can activate complement via the alternative or lectin
pathway. The pattern of glycosylation of IgA1 and the molecular mass of IgA1-containing immune …
pathway. The pattern of glycosylation of IgA1 and the molecular mass of IgA1-containing immune …
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