Relationship between left ventricular structural and metabolic remodeling in type 2 diabetes

E Levelt, M Mahmod, SK Piechnik, R Ariga… - Diabetes, 2016 - Am Diabetes Assoc
… of diabetic cardiomyopathy (17). The role of interstitial fibrosis in the pathogenesis of LV
hypertrophy in stable/early diabetic cardiomyopathy is … Cardiac magnetic resonance (CMR) T1 …

Right ventricular dysfunction and remodeling in diabetic cardiomyopathy

Y Kang, S Wang, J Huang, L Cai… - … of Physiology-Heart …, 2019 - journals.physiology.org
… The increasing prevalence of diabetic cardiomyopathy (DCM) is an important threat to health
worldwide. While left ventricular (LV) dysfunction in DCM is well recognized, the accurate …

Diabetic cardiomyopathy and metabolic remodeling of the heart

PK Battiprolu, C Lopez-Crisosto, ZV Wang… - Life sciences, 2013 - Elsevier
… are unique, raising the prospect of diabetes-specific therapeutic intervention. Here, we …
the pathogenesis of diabetic cardiomyopathy and associated metabolic remodeling with an eye …

Overexpression of human C-reactive protein exacerbates left ventricular remodeling in diabetic cardiomyopathy

Y Mano, T Anzai, H Kaneko, Y Nagatomo… - Circulation …, 2011 - jstage.jst.go.jp
… We hypothesized that CRP overexpression might worsen diabetic cardiomyopathy
through … diabetic cardiomyopathy using human CRP-overexpressing transgenic mice (CRP-Tg). …

[HTML][HTML] Cardiomyocyte-specific knockout of ADAM17 ameliorates left ventricular remodeling and function in diabetic cardiomyopathy of mice

F Xue, J Cheng, Y Liu, C Cheng, M Zhang… - … and Targeted Therapy, 2022 - nature.com
… beneficial in attenuating diabetic cardiomyopathy (DCM) but … α-MHCKO ) mice, and left
ventricular dimension, function, … , ADAM17 fl/fl diabetic and A17 α-MHCKO diabetic mice. Both …

[HTML][HTML] The diabetic cardiomyopathy: the contributing pathophysiological mechanisms

T Salvatore, PC Pafundi, R Galiero, G Albanese… - Frontiers in …, 2021 - frontiersin.org
… receptor type 2 (CCR2) (178), and macrophages derived from CCR 2+ monocytes are
required for adverse left ventricle remodeling (179). A recent study on mice demonstrated that the …

Angiotensin-converting enzyme-2 overexpression improves left ventricular remodeling and function in a rat model of diabetic cardiomyopathy

B Dong, QT Yu, HY Dai, YY Gao, ZL Zhou… - … the American College of …, 2012 - jacc.org
cardiomyopathy. Thus, ACE2 provides a promising approach to the treatment of patients
with diabetic cardiomyopathyDiabetic cardiomyopathy (DCM) is characterized by a variety of …

[HTML][HTML] Left ventricular hypertrophy in diabetic cardiomyopathy: a target for intervention

M Mohan, A Dihoum, IR Mordi, AM Choy… - Frontiers in …, 2021 - frontiersin.org
… is a good surrogate marker of diabetic cardiomyopathy and discussed the trials targeting
LVH as a manifestation of Stage B Cardiomyopathy, and potential mechanisms behind LVH …

[HTML][HTML] LAZ3 protects cardiac remodeling in diabetic cardiomyopathy via regulating miR-21/PPARa signaling

L Gao, Y Liu, S Guo, L Xiao, L Wu, Z Wang… - … BBA)-Molecular Basis of …, 2018 - Elsevier
… and the pathogenesis of cardiac remodeling that can lead to heart failure. We aimed to …
in diabetic cardiomyopathy (DCM). Streptozotocin (STZ) was used to induce a diabetic mouse …

Predictors and prevention of diabetic cardiomyopathy

V Chavali, SC Tyagi, PK Mishra - Diabetes, metabolic syndrome …, 2013 - Taylor & Francis
… increased apoptosis, a slight increase in left ventricular size, and diastolic dysfunction and …
in left ventricular size, and a decrease in cardiac performance leading to heart failure. Recent …