[HTML][HTML] The safety and efficacy of lenvatinib combined with immune checkpoint inhibitors therapy for advanced hepatocellular carcinoma

Y Wang, M Jiang, J Zhu, J Qu, K Qin, D Zhao… - Biomedicine & …, 2020 - Elsevier
… , so most patients are focused on a targeted treatment and immune checkpoint inhibitors [5,7]. …
checkpoint inhibitors is also a hot spot in recent research. At present, the combination of …

Lenvatinib with or without immune checkpoint inhibitors for patients with unresectable hepatocellular carcinoma in real-world clinical practice

K Chen, W Wei, L Liu, ZJ Deng, L Li, XM Liang… - Cancer Immunology …, 2021 - Springer
Lenvatinib is regarded as the first-line therapy for patients with unresectable hepatocellular
… and safety of lenvatinib with or without immune checkpoint inhibitors (ICIs) in patients with …

[HTML][HTML] Lenvatinib plus immune checkpoint inhibitors improve survival in advanced hepatocellular carcinoma: a retrospective study

X Huang, L Xu, T Ma, X Yin, Z Huang, Y Ran… - Frontiers in …, 2021 - frontiersin.org
patients with advanced hepatocellular carcinoma who were treated with lenvatinib plus immune
checkpoint inhibitors. … In this study, the combination of lenvatinib plus ICIs improved both …

Exploratory analysis of lenvatinib therapy in patients with unresectable hepatocellular carcinoma who have failed prior PD− 1/PD-L1 checkpoint blockade

T Aoki, M Kudo, K Ueshima, M Morita, H Chishina… - Cancers, 2020 - mdpi.com
… on PD−1/PD-L1 blockade is unknown. In this work, we evaluated the safety and efficacy of
lenvatinib administration after PD-1/PD-L1 checkpoint blockade. The outcome and safety of …

… on therapeutic efficacy of transarterial chemoembolization combined with immune checkpoint inhibitors plus lenvatinib in patients with unresectable hepatocellular …

Y Teng, X Ding, W Li, W Sun… - Technology in Cancer …, 2022 - journals.sagepub.com
lenvatinib plus anti-PD-1 inhibitors may achieve greater therapeutic benefits for uHCC patients.
… efficacy and safety of TACE combined with lenvatinib plus anti-PD-1 inhibitors for uHCC. …

Combining immune checkpoint inhibitor with lenvatinib prolongs survival than lenvatinib alone in sorafenib-experienced hepatocellular carcinoma patients

PT Lin, W Teng, WJ Jeng, CY Lin, SM Lin… - European Journal of …, 2022 - journals.lww.com
patients, the clinical benefit of combining ICI with lenvatinibpatient receiving lenvatinib
and whether the combining ICI with lenvatinib provides a greater survival benefit than lenvatinib

[HTML][HTML] Phase II study of lenvatinib plus pembrolizumab for disease progression after PD-1/PD-L1 immune checkpoint inhibitor in metastatic clear cell renal cell …

CH Lee, AY Shah, V Makker, MH Taylor, D Shaffer… - Annals of …, 2019 - Elsevier
Lenvatinib (LEN) is a multikinase VEGFR inhibitor approved for use in combination with …
specifically in patients (pts) who progressed with prior immune checkpoint inhibitor (ICI) therapy. …

Lenvatinib with or without everolimus in patients with metastatic renal cell carcinoma after immune checkpoint inhibitors and vascular endothelial growth factor …

AJ Wiele, TK Bathala, AW Hahn, L Xiao, M Duran… - The …, 2021 - academic.oup.com
… of lenvatinib plus everolimus for patients with ccRCC or nccRCC [28]. Our cohort included
42 patients who received lenvatinib plus everolimus and 13 patients who received lenvatinib

Lenvatinib plus checkpoint inhibitors in patients (pts) with advanced intrahepatic cholangiocarcinoma (ICC): Preliminary data and correlation with next-generation …

J Lin, W Shi, S Zhao, J Hu, Z Hou, M Yao, G Chrin… - 2018 - ascopubs.org
500 Background: Lenvatinib (Len) is a multikinase inhibitor targeting VEGFR 1-3, FGFR 1-4
and other kinases. Pembrolizumab (Pem) and nivolumab (Nivo) are antibodies inhibiting

Effectiveness of lenvatinib plus immune checkpoint inhibitors in primary advanced hepatocellular carcinoma beyond oligometastasis

XH Wang, CJ Liu, HQ Wen, XH Duan… - Clinical and …, 2023 - Wiley Online Library
lenvatinib and PD-1 inhibitor at the same time, or patients who received PD-1 inhibitor within
1 week of lenvatinib … (TP), patients treated with PD-1 inhibitors after more than 3 months of …