… such as type 1 diabetes mellitus or obesity, … leptin synthesis by adipose tissue, and the
amount of expression of membrane-anchored, signal-transducing leptin receptors (OB-Rs), leptin …

… 2 diabetes mellitus (T2DM) research are the congenital leptin… the most common leptin/leptin
receptor-based animal models … caused by abnormal leptin/leptin receptor signaling with the …

… Background: Global increase in the prevalence of type 2 diabetes mellitus (T2DM) … of
diabetes. Recent studies have drawn attention to the role of leptin (LEP) and leptin receptor (LEPR) …

… a relationship between leptin receptor (LEPR) gene polymorphism and type 2 diabetes mellitus
(… This meta-analysis was designed to assess a more accurate association between LEPR …

… We measured serum levels of free leptin, bound leptin, and soluble leptin receptor by specific
RIA methods in 20 normal and 19 insulin-dependent diabetes mellitus subjects at 20 and …

… mellitus (GDM) patients and normal glucose tolerance (NGT) individuals and also to explore
… of leptin (LEP) G2548A and leptin receptor (LEPR) Gln223Arg polymorphisms with leptin …

… the pattern of leptin receptor gene polymorphism Gln223Arg in T2DM and to identify its
association with the serum leptin and insulin levels as well as with insulin resistance in diabetes. …

… of the LEP and LEPR polymorphisms on metabolic traits and their relationship to T2DM. We
screened 15 polymorphisms in the leptin and leptin receptor genes and determined whether …

… Moreover, it is believed that leptin level deductions might be the cause of obesity … 2 Diabetes
Mellitus (T2DM), as well as in cardiovascular diseases (CVD). The Leptin Receptor (LEPR) …

… genetic variants of leptin and leptin receptor (LEPR) genes, … LEPR polymorphisms in
centenarians and in control groups. Material and methods: The frequencies of the LEP and LEPR …