Gene polymorphisms of adiponectin and leptin receptor are associated with early onset of type 2 diabetes mellitus in the Taiwanese population

WL Liao, CC Chen, CT Chang, JY Wu… - International journal of …, 2012 - nature.com
… , leptin also has a critical role in the regulation of fat metabolism. Leptin prevents obesity by
acting on leptin receptors to … Additionally, leptin and its receptor inhibit insulin secretion by …

Leptin and leptin receptor gene polymorphisms and their association with plasma leptin levels and obesity in a multi-ethnic Malaysian suburban population

SH Fan, YH Say - Journal of physiological anthropology, 2014 - Springer
… The LEP and LEPR SNPs in this study may not be an obesity marker among Malaysians
in this population, but were associated with ethnicity. Our findings suggest that each of these …

G‐2548A Polymorphism of the Leptin Gene Is Correlated with Extreme Obesity in Taiwanese Aborigines

TN Wang, MC Huang, WT Chang, AMS Ko, EM Tsai… - …, 2006 - Wiley Online Library
… The leptin receptor, also identified as the diabetes gene … markers near the leptin (LEP) 1
and leptin receptor (LEPR) gene … study (5) and a Pennsylvanian population (6) but not in Pima …

Association of leptin receptor polymorphism with insulin resistance

KC Chiu, A Chu, LM Chuang… - European Journal of …, 2004 - academic.oup.com
… of Q223R polymorphism at the leptin receptor gene has been … Interestingly, just like our
population in this study, most of the … age ,30 years old) and healthy populations (14, 16, 19). In …

The roles of serum leptin concentration and polymorphism in leptin receptor gene at codon 109 in breast cancer

CL Liu, YC Chang, SP Cheng, SR Chern, TL Yang… - Oncology, 2007 - karger.com
… between the serum leptin/adiponectin ratio and tumor size in Taiwanese patients with … :
Leptin receptor gene variation and obesity: lack of association in a white British male population. …

Modification effect of sex and obesity on the correlation of LEP polymorphisms with leptin levels in Taiwanese obese women

DM Duan, JY Jhang, S Wu, MS Teng… - Molecular genetics & …, 2020 - Wiley Online Library
… In the general population, circulating leptin level was significantly and positively correlated
with BMI, waist circumference, systolic blood pressure, insulin, HOMA-IR index, and CRP …

Leptin expression and leptin receptor gene polymorphisms in growth hormone deficiency patients

PH Su, JY Chen, JS Yu, SJ Chen, SF Yang - Human genetics, 2011 - Springer
leptin associations with GHD in various populations is that polymorphisms of the leptin (LEP)
or the leptin receptor (LEPR… These Taiwanese children with GHD had significantly lower BA/…

Leptin levels and leptin receptor polymorphism frequency in healthy populations

CC Ragin, C Dallal, M Okobia, F Modugno… - Infectious Agents and …, 2009 - Springer
… In this study, we have determined the frequency of leptin receptor polymorphism (LEPR
Q223R) in healthy populations from various ethnic groups (African, African-American, African-…

Clinicopathologic significance of leptin and leptin receptor expressions in papillary thyroid carcinoma

SP Cheng, CW Chi, CY Tzen, TL Yang, JJ Lee, TP Liu… - Surgery, 2010 - Elsevier
… Expression of leptin and/or leptin receptor in papillary thyroid cancer is associated with … to
be associated with greater mortality in a large population-based study, 4 although the role of …

Leptin− 2548 G/A polymorphisms are associated to clinical progression of oral cancer and sensitive to oral tumorization in nonsmoking population

WC Hung, CM Tsai, CW Lin, CY Chuang… - Journal of Cellular …, 2019 - Wiley Online Library
Leptin (LEP) and leptin receptor (LEPR) both play a crucial role in the mediation of … with
oral cancer and 560 healthy controls in Taiwan were analyzed. The results shown that the …